Receptor activator of NF-κB ligand effect on bone marrow-derived macrophage cells: time course
Summary:
Analysis of bone marrow-derived macrophages (BMMs) collected from 6-8 week old C57BL/6 animals and treated with receptor activator of NF-κB ligand (RANKL) for up to 3 days. Results provide insight into the molecular mechanisms underlying RANKL-mediated induction of osteoclastogenesis.
An D, Kim K, Lu W. Defective entry into mitosis 1 (Dim1) negatively regulates osteoclastogenesis by inhibiting the expression of nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 (NFATc1). J Biol Chem 2014 Aug 29;289(35):24366-73. PMID: 25023277
