DataSet Record GDS5661: Expression Profiles Data Analysis Tools Sample Subsets
Title: Interleukin 7 and FLT-3 ligand effect on EML1 HSPC line expressing acute lymphoblastic leukemia TEL-AML1 fusion protein: time course
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Summary: Analysis of TEL-AML1 oncogene-expressing hematopoietic stem/progenitor cell line EML1 treated with interleukin 7 (IL7) and FLT3 ligand (FLT3L) for up to 7 days. IL7 and FLT3L treatment induces B-cell differentiation. Results provide insight into the role of TEL-AML1 in early B-cell differentiation.
Organism: Mus musculus
Platform: GPL11533: [MoGene-1_1-st] Affymetrix Mouse Gene 1.1 ST Array [transcript (gene) version]
Citation:
  • de Laurentiis A, Hiscott J, Alcalay M. The TEL-AML1 fusion protein of acute lymphoblastic leukemia modulates IRF3 activity during early B-cell differentiation. Oncogene 2015 Dec 3;34(49):6018-28. PMID: 25893288
Reference Series: GSE64919 Sample count: 12
Value type: count Series published: 2015/05/13