MicroRNA-135b overexpression effect on prostate cancer cell line: time course
Summary:
Analysis of LNCaP prostate cancer (PCa) cells overexpressing miRNA-135b for up to 36 hours. LNCaP cells express the androgen receptor (AR). MiRNA-135b overexpression in AR+ PCa cells results in slower growth compared to AR knockdown. Results provide insight into the basis of this slower growth.
Aakula A, Leivonen SK, Hintsanen P, Aittokallio T et al. MicroRNA-135b regulates ERα, AR and HIF1AN and affects breast and prostate cancer cell growth. Mol Oncol 2015 Aug;9(7):1287-300. PMID: 25907805
