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    PLB1 phospholipase B1 [ Oryctolagus cuniculus (rabbit) ]

    Gene ID: 100009309, updated on 17-Dec-2024

    Summary

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    Gene symbol
    PLB1
    Gene description
    phospholipase B1
    See related
    Ensembl:ENSOCUG00000015168
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Oryctolagus cuniculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
    Also known as
    PHLPB
    Orthologs
    human mouse all
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    Genomic context

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    See PLB1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    62
    Annotation release Status Assembly Chr Location
    RS_2024_11 current mOryCun1.1 (GCF_964237555.1) 2 NC_091433.1 (174332336..174470204, complement)
    RS_2023_02 previous assembly UM_NZW_1.0 (GCF_009806435.1) 2 NC_067375.1 (157735626..157860182, complement)

    Chromosome 2 - NC_091433.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC138848645 Neighboring gene uncharacterized LOC138848646 Neighboring gene FOS like 2, AP-1 transcription factor subunit Neighboring gene BRISC and BRCA1 A complex member 2 Neighboring gene U2 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Messenger RNAs expressed in intestine of adult but not baby rabbits. Isolation of cognate cDNAs and characterization of a novel brush border protein with esterase and phospholipase activity. Boll W, et al. J Biol Chem, 1993 Jun 15. PMID 8509424
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables lysophospholipase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phospholipase A2 activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables retinyl-palmitate esterase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in phospholipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in brush border membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    phospholipase B1, membrane-associated
    Names
    PLB/LIP
    lysophospholipase
    phospholipase A2
    phospholipase AdRab-B
    phospholipase B
    phospholipase B/lipase
    triacylglycerol lipase
    NP_001095178.1
    XP_051684699.2
    XP_051684705.2
    XP_051684721.2
    XP_069923999.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001101708.1 → NP_001095178.1  phospholipase B1, membrane-associated precursor

      See identical proteins and their annotated locations for NP_001095178.1

      Status: PROVISIONAL

      Source sequence(s)
      Z12841
      UniProtKB/Swiss-Prot
      Q05017
      UniProtKB/TrEMBL
      G1T8Y1
      Related
      ENSOCUP00000013064.4, ENSOCUT00000015201.4
      Conserved Domains (2) summary
      cd01824
      Location:382 → 677
      Phospholipase_B_like; Phospholipase-B_like. This subgroup of the SGNH-family of lipolytic enzymes may have both esterase and phospholipase-A/lysophospholipase activity. It's members may be involved in the conversion of phosphatidylcholine to fatty acids and ...
      cl01053
      Location:61 → 317
      SGNH_hydrolase; SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely ...

    RefSeqs of Annotated Genomes: GCF_964237555.1-RS_2024_11

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mOryCun1.1

    Genomic

    1. NC_091433.1 Reference mOryCun1.1

      Range
      174332336..174470204 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_070067898.1 → XP_069923999.1  phospholipase B1, membrane-associated isoform X3

      UniProtKB/TrEMBL
      G1T8Y1

    2. XM_051828745.2 → XP_051684705.2  phospholipase B1, membrane-associated isoform X2

      UniProtKB/TrEMBL
      G1T8Y1

    3. XM_051828739.2 → XP_051684699.2  phospholipase B1, membrane-associated isoform X1

      UniProtKB/TrEMBL
      G1T8Y1

    4. XM_051828761.2 → XP_051684721.2  phospholipase B1, membrane-associated isoform X4

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q05017.1 GenPept UniProtKB/Swiss-Prot:Q05017

    Gene LinkOut

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