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    GRD GABA-gated ion channel GRD [ Nasonia vitripennis (jewel wasp) ]

    Gene ID: 100121127, updated on 10-Oct-2024

    Summary

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    Gene symbol
    GRD
    Gene description
    GABA-gated ion channel GRD
    See related
    NASONIABASE:NV15598
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Nasonia vitripennis
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Hymenoptera; Apocrita; Proctotrupomorpha; Chalcidoidea; Pteromalidae; Pteromalinae; Nasonia
    Orthologs
    fruit fly honey bee all
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    Genomic context

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    See GRD in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    104 current Nvit_psr_1.1 (GCF_009193385.2) 3 Unlocalized Scaffold NC_045759.1 (23768146..23775798, complement)
    103 previous assembly Nvit_psr_1 (GCF_009193385.1) 3 Unlocalized Scaffold NW_022279634.1 (984314..991966)

    Chromosome 3 - NC_045759.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100121075 Neighboring gene uncharacterized LOC100678587 Neighboring gene uncharacterized LOC103316131 Neighboring gene farnesol dehydrogenase Neighboring gene arylsulfatase B Neighboring gene golgin subfamily B member 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The cys-loop ligand-gated ion channel gene superfamily of the parasitoid wasp, Nasonia vitripennis. Jones AK, et al. Heredity (Edinb), 2010 Mar. PMID 20087392
    2. Functional and evolutionary insights from the genomes of three parasitoid Nasonia species. Werren JH, et al. Science, 2010 Jan 15. PMID 20075255, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GABA-A receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables extracellular ligand-gated monoatomic ion channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables neurotransmitter receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in monoatomic ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nervous system process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of membrane potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    GABA-gated ion channel; GABA-gated ion channel GRD

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001247958.1 → NP_001234887.1  GABA-gated ion channel precursor

      See identical proteins and their annotated locations for NP_001234887.1

      Status: PROVISIONAL

      Source sequence(s)
      FJ851092
      UniProtKB/TrEMBL
      D3UAF3
      Conserved Domains (3) summary
      TIGR00860
      Location:43 → 437
      LIC; Cation transporter family protein
      pfam02931
      Location:51 → 260
      Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
      pfam02932
      Location:267 → 434
      Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region

    RefSeqs of Annotated Genomes: Nasonia vitripennis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Nvit_psr_1.1

    Genomic

    1. NC_045759.1 Reference Nvit_psr_1.1

      Range
      23768146..23775798 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008207939.4 → XP_008206161.1  GABA-gated ion channel GRD isoform X4

      See identical proteins and their annotated locations for XP_008206161.1

      UniProtKB/TrEMBL
      A0A7M7H9W3
      Conserved Domains (3) summary
      TIGR00860
      Location:45 → 439
      LIC; Cation transporter family protein
      pfam02931
      Location:53 → 262
      Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
      pfam02932
      Location:269 → 436
      Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region

    2. XM_008207938.4 → XP_008206160.1  GABA-gated ion channel GRD isoform X4

      See identical proteins and their annotated locations for XP_008206160.1

      UniProtKB/TrEMBL
      A0A7M7H9W3
      Conserved Domains (3) summary
      TIGR00860
      Location:45 → 439
      LIC; Cation transporter family protein
      pfam02931
      Location:53 → 262
      Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
      pfam02932
      Location:269 → 436
      Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region

    3. XM_032597724.1 → XP_032453615.1  GABA-gated ion channel GRD isoform X5

      UniProtKB/TrEMBL
      A0A7M7QVX5
      Conserved Domains (2) summary
      TIGR00860
      Location:45 → 434
      LIC; Cation transporter family protein
      cd19007
      Location:75 → 256
      LGIC_ECD_GABAR_GRD-like; gamma-aminobutyric acid receptor subunit alpha-like extracellular domain in protostomia, such as GRD (GABA/glycine-like receptor of Drosophila)

    4. XM_031927186.2 → XP_031783046.1  GABA-gated ion channel GRD isoform X2

      UniProtKB/TrEMBL
      A0A7M7Q7T0
      Conserved Domains (2) summary
      TIGR00860
      Location:137 → 526
      LIC; Cation transporter family protein
      cd19007
      Location:167 → 348
      LGIC_ECD_GABAR_GRD-like; gamma-aminobutyric acid receptor subunit alpha-like extracellular domain in protostomia, such as GRD (GABA/glycine-like receptor of Drosophila)

    5. XM_031927187.2 → XP_031783047.1  GABA-gated ion channel GRD isoform X3

      UniProtKB/TrEMBL
      A0A7M7T8S2
      Conserved Domains (2) summary
      TIGR00860
      Location:128 → 522
      LIC; Cation transporter family protein
      cd19007
      Location:158 → 344
      LGIC_ECD_GABAR_GRD-like; gamma-aminobutyric acid receptor subunit alpha-like extracellular domain in protostomia, such as GRD (GABA/glycine-like receptor of Drosophila)

    6. XM_031927185.2 → XP_031783045.1  GABA-gated ion channel GRD isoform X1

      UniProtKB/TrEMBL
      A0A7M7T8S5
      Conserved Domains (2) summary
      TIGR00860
      Location:137 → 531
      LIC; Cation transporter family protein
      cd19007
      Location:167 → 353
      LGIC_ECD_GABAR_GRD-like; gamma-aminobutyric acid receptor subunit alpha-like extracellular domain in protostomia, such as GRD (GABA/glycine-like receptor of Drosophila)
    Nucleotide Protein Strain
    Heading Accession and Version

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