U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    stat2 signal transducer and activator of transcription 2 [ Salmo salar (Atlantic salmon) ]

    Gene ID: 100270812, updated on 11-Apr-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    stat2
    Gene description
    signal transducer and activator of transcription 2
    See related
    Ensembl:ENSSSAG00000067332
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Salmo salar
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes; Salmonidae; Salmoninae; Salmo
    Also known as
    STAT3; STAT2a; STAT2b
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    zebrafish all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See stat2 in Genome Data Viewer
    Location:
    chromosome: ssa12
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    102 current Ssal_v3.1 (GCF_905237065.1) ssa12 NC_059453.1 (66635278..66647159)
    100 previous assembly ICSASG_v2 (GCF_000233375.1) ssa12 NC_027311.1 (58670994..58682874)

    Chromosome ssa12 - NC_059453.1Genomic Context describing neighboring genes Neighboring gene core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, like b Neighboring gene uncharacterized LOC106565525 Neighboring gene G-protein coupled receptor 84-like Neighboring gene zinc finger protein 385A

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Isolation and expression profile of a gene encoding for the Signal Transducer and Activator of Transcription STAT2 in Atlantic salmon (Salmo salar). Collet B, et al. Dev Comp Immunol, 2009 Jul. PMID 19428483
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The full length cDNA sequence of Atlantic salmon (Salmo salar) ssSTAT2 was determined and phylogenetic analysis of the amino acid sequence grouped this novel salmon gene to the STAT2 clade.
      Title: Isolation and expression profile of a gene encoding for the Signal Transducer and Activator of Transcription STAT2 in Atlantic salmon (Salmo salar).
    Submit: New GeneRIF Correction

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell surface receptor signaling pathway via JAK-STAT IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in defense response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell population proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to peptide hormone IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in type I interferon-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    signal transducer and activator of transcription 2
    Names
    Signal transducer and activator of transcription 3

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001145424.1 → NP_001138896.1  signal transducer and activator of transcription 2

      See identical proteins and their annotated locations for NP_001138896.1

      Status: PROVISIONAL

      Source sequence(s)
      FJ173070
      UniProtKB/TrEMBL
      B9UYM8, X2KK07
      Related
      ENSSSAP00000081094.2, ENSSSAT00000114788.2
      Conserved Domains (4) summary
      pfam01017
      Location:168 → 304
      STAT_alpha; STAT protein, all-alpha domain
      pfam02864
      Location:306 → 554
      STAT_bind; STAT protein, DNA binding domain
      pfam02865
      Location:2 → 121
      STAT_int; STAT protein, protein interaction domain
      cl15255
      Location:545 → 688
      SH2; Src homology 2 (SH2) domain

    RefSeqs of Annotated Genomes: Salmo salar Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Ssal_v3.1

    Genomic

    1. NC_059453.1 Reference Ssal_v3.1

      Range
      66635278..66647159
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.