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    ERVK-9 endogenous retrovirus group K member 9 [ Homo sapiens (human) ]

    Gene ID: 100616102, updated on 14-Nov-2024

    Summary

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    Official Symbol
    ERVK-9provided by HGNC
    Official Full Name
    endogenous retrovirus group K member 9provided by HGNC
    Primary source
    HGNC:HGNC:39005
    Gene type
    other
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    PR; Protease; Proteinase; polymerase
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    Genomic context

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    Location:
    6q14.1

    Bibliography

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    Related articles in PubMed

    1. Identification of an active reverse transcriptase enzyme encoded by a human endogenous HERV-K retrovirus. Berkhout B, et al. J Virol, 1999 Mar. PMID 9971820, Free PMC Article
    2. Human endogenous retrovirus HERV-K(HML-2) proviruses with Rec protein coding capacity and transcriptional activity. Mayer J, et al. Virology, 2004 Apr 25. PMID 15063128
    3. Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project. Flockerzi A, et al. BMC Genomics, 2008 Jul 29. PMID 18664271, Free PMC Article
    4. Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution. Blaise S, et al. Proc Natl Acad Sci U S A, 2003 Oct 28. PMID 14557543, Free PMC Article
    5. A revised nomenclature for transcribed human endogenous retroviral loci. Mayer J, et al. Mob DNA, 2011 May 4. PMID 21542922, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Other Names

    • Endogenous retrovirus group K member 9 Env polyprotein
    • Endogenous retrovirus group K member 9 Gag polyprotein
    • Endogenous retrovirus group K member 9 Pro protein
    • EnvK4 protein
    • Envelope polyprotein
    • Gag polyprotein
    • HERV-K(C6) Gag protein
    • HERV-K(C6) Pro protein
    • HERV-K(C6) envelope protein
    • HERV-K109 Gag protein
    • HERV-K109 Pro protein
    • HERV-K109 envelope protein
    • HERV-K_6q14.1 provirus ancestral Env polyprotein
    • HERV-K_6q14.1 provirus ancestral Gag polyprotein
    • HERV-K_6q14.1 provirus ancestral Gag-Pol polyprotein
    • HERV-K_6q14.1 provirus ancestral Pro protein

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables aspartic-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural molecule activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    NOT involved_in syncytium formation by plasma membrane fusion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in viral translational frameshifting IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P63126.2 GenPept UniProtKB/Swiss-Prot:P63126
    P63127.1 GenPept UniProtKB/Swiss-Prot:P63127
    Q9UKH3.1 GenPept UniProtKB/Swiss-Prot:Q9UKH3

    Gene LinkOut

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