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    Slit1 slit guidance ligand 1 [ Cricetulus griseus (Chinese hamster) ]

    Gene ID: 100756902, updated on 8-Mar-2024

    Summary

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    Gene symbol
    Slit1
    Gene description
    slit guidance ligand 1
    Locus tag
    I79_003408
    See related
    Ensembl:ENSCGRG00015025043
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cricetulus griseus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
    Orthologs
    human mouse all
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    Genomic context

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    See Slit1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    37
    Annotation release Status Assembly Chr Location
    104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003613664.1 (981687..1131968, complement)
    104 current CriGri-PICRH-1.0 (GCF_003668045.3) 3 NC_048596.1 (19817609..19968230)

    NW_003613664.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L30-like Neighboring gene ligand dependent nuclear receptor corepressor Neighboring gene c-Myc-binding protein-like Neighboring gene U6 spliceosomal RNA Neighboring gene DET1- and DDB1-associated protein 1 Neighboring gene thymosin beta-4-like Neighboring gene Rho GTPase activating protein 19

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables Roundabout binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables heparin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in axon guidance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative chemotaxis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    slit homolog 1 protein
    Names
    Slit-like 1 protein
    slit homolog 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference CriGri_1.0 Primary Assembly

    Genomic

    1. NW_003613664.1 Reference CriGri_1.0 Primary Assembly

      Range
      981687..1131968 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_007617144.4 → XP_007615334.1  slit homolog 1 protein

      UniProtKB/TrEMBL
      G3GZW0
      Conserved Domains (9) summary
      smart00013
      Location:33 → 64
      LRRNT; Leucine rich repeat N-terminal domain
      smart00082
      Location:866 → 915
      LRRCT; Leucine rich repeat C-terminal domain
      smart00282
      Location:1186 → 1319
      LamG; Laminin G domain
      cd00054
      Location:1085 → 1119
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00116
      Location:87 → 220
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:43 → 62
      LRR_RI; leucine-rich repeat [structural motif]
      pfam12799
      Location:334 → 373
      LRR_4; Leucine Rich repeats (2 copies)
      pfam13855
      Location:590 → 649
      LRR_8; Leucine rich repeat
      cl15307
      Location:439 → 469
      TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain

    Alternate CriGri-PICRH-1.0

    Genomic

    1. NC_048596.1 Alternate CriGri-PICRH-1.0

      Range
      19817609..19968230
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_027407335.2 → XP_027263136.1  slit homolog 1 protein

      UniProtKB/TrEMBL
      A0A8C2M3S5, G3GZW0
      Related
      ENSCGRP00015033335.1, ENSCGRT00015040665.2
    Nucleotide Protein Strain
    Heading Accession and Version

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