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    RASAL2 RAS protein activator like 2 [ Condylura cristata (star-nosed mole) ]

    Gene ID: 101632667, updated on 8-Mar-2024

    Summary

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    Gene symbol
    RASAL2
    Gene description
    RAS protein activator like 2
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Condylura cristata
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Eulipotyphla; Talpidae; Condylura
    Orthologs
    human mouse all
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    Genomic context

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    See RASAL2 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    101 current ConCri1.0 (GCF_000260355.1) Unplaced Scaffold NW_004567125.1 (21626195..21933995)

    NW_004567125.1Genomic Context describing neighboring genes Neighboring gene SEC16 homolog B, endoplasmic reticulum export factor Neighboring gene quinone oxidoreductase-like protein 2 Neighboring gene C-type lectin domain containing 20A Neighboring gene testis expressed 35

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_004567125.1 Unplaced Scaffold Reference ConCri1.0

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ras GTPase-activating protein nGAP

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Condylura cristata Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ConCri1.0

    Genomic

    1. NW_004567125.1 Reference ConCri1.0

      Range
      21626195..21933995
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_012729032.1 → XP_012584486.1  ras GTPase-activating protein nGAP isoform X1

      Conserved Domains (6) summary
      cd04013
      Location:307 → 446
      C2_SynGAP_like; C2 domain present in Ras GTPase activating protein (GAP) family
      cd05136
      Location:437 → 767
      RasGAP_DAB2IP; Ras-GTPase Activating Domain of DAB2IP and similar proteins
      smart00323
      Location:430 → 768
      RasGAP; GTPase-activator protein for Ras-like GTPases
      cd13373
      Location:184 → 321
      PH_nGAP; Neuronal growth-associated proteins Pleckstrin homology (PH) domain
      pfam12004
      Location:757 → 1235
      DUF3498; Domain of unknown function (DUF3498)
      cl02488
      Location:1113 → 1252
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

    2. XM_012729034.1 → XP_012584488.1  ras GTPase-activating protein nGAP isoform X3

      Conserved Domains (6) summary
      cd04013
      Location:307 → 446
      C2_SynGAP_like; C2 domain present in Ras GTPase activating protein (GAP) family
      cd05136
      Location:437 → 767
      RasGAP_DAB2IP; Ras-GTPase Activating Domain of DAB2IP and similar proteins
      smart00323
      Location:430 → 768
      RasGAP; GTPase-activator protein for Ras-like GTPases
      pfam12004
      Location:757 → 1251
      DUF3498; Domain of unknown function (DUF3498)
      cl02488
      Location:1113 → 1261
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cl17171
      Location:182 → 365
      PH-like; Pleckstrin homology-like domain

    3. XM_012729033.1 → XP_012584487.1  ras GTPase-activating protein nGAP isoform X2

      Conserved Domains (6) summary
      cd04013
      Location:307 → 446
      C2_SynGAP_like; C2 domain present in Ras GTPase activating protein (GAP) family
      cd05136
      Location:437 → 767
      RasGAP_DAB2IP; Ras-GTPase Activating Domain of DAB2IP and similar proteins
      smart00323
      Location:430 → 768
      RasGAP; GTPase-activator protein for Ras-like GTPases
      cd13373
      Location:184 → 321
      PH_nGAP; Neuronal growth-associated proteins Pleckstrin homology (PH) domain
      pfam12004
      Location:757 → 1233
      DUF3498; Domain of unknown function (DUF3498)
      cl02488
      Location:1111 → 1250
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

    4. XM_004688511.2 → XP_004688568.1  ras GTPase-activating protein nGAP isoform X4

      Conserved Domains (6) summary
      cd04013
      Location:307 → 446
      C2_SynGAP_like; C2 domain present in Ras GTPase activating protein (GAP) family
      cd05136
      Location:437 → 767
      RasGAP_DAB2IP; Ras-GTPase Activating Domain of DAB2IP and similar proteins
      smart00323
      Location:430 → 768
      RasGAP; GTPase-activator protein for Ras-like GTPases
      pfam12004
      Location:757 → 1249
      DUF3498; Domain of unknown function (DUF3498)
      cl02488
      Location:1111 → 1259
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cl17171
      Location:182 → 365
      PH-like; Pleckstrin homology-like domain

    5. XM_012729035.1 → XP_012584489.1  ras GTPase-activating protein nGAP isoform X5

      Conserved Domains (6) summary
      cd04013
      Location:307 → 446
      C2_SynGAP_like; C2 domain present in Ras GTPase activating protein (GAP) family
      cd05136
      Location:437 → 760
      RasGAP_DAB2IP; Ras-GTPase Activating Domain of DAB2IP and similar proteins
      smart00323
      Location:430 → 761
      RasGAP; GTPase-activator protein for Ras-like GTPases
      cd13373
      Location:184 → 321
      PH_nGAP; Neuronal growth-associated proteins Pleckstrin homology (PH) domain
      pfam12004
      Location:750 → 1228
      DUF3498; Domain of unknown function (DUF3498)
      cl02488
      Location:1106 → 1245
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

    6. XM_004688512.2 → XP_004688569.1  ras GTPase-activating protein nGAP isoform X6

      Conserved Domains (6) summary
      cd04013
      Location:307 → 446
      C2_SynGAP_like; C2 domain present in Ras GTPase activating protein (GAP) family
      cd05136
      Location:437 → 760
      RasGAP_DAB2IP; Ras-GTPase Activating Domain of DAB2IP and similar proteins
      smart00323
      Location:430 → 761
      RasGAP; GTPase-activator protein for Ras-like GTPases
      pfam12004
      Location:750 → 1242
      DUF3498; Domain of unknown function (DUF3498)
      cl02488
      Location:1104 → 1252
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cl17171
      Location:182 → 365
      PH-like; Pleckstrin homology-like domain

    7. XM_004688513.2 → XP_004688570.1  ras GTPase-activating protein nGAP isoform X10

      Conserved Domains (6) summary
      cd04013
      Location:159 → 298
      C2_SynGAP_like; C2 domain present in Ras GTPase activating protein (GAP) family
      cd05136
      Location:289 → 619
      RasGAP_DAB2IP; Ras-GTPase Activating Domain of DAB2IP and similar proteins
      smart00323
      Location:282 → 620
      RasGAP; GTPase-activator protein for Ras-like GTPases
      pfam12004
      Location:609 → 1101
      DUF3498; Domain of unknown function (DUF3498)
      cl02488
      Location:963 → 1111
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cl17171
      Location:34 → 217
      PH-like; Pleckstrin homology-like domain

    8. XM_012729037.1 → XP_012584491.1  ras GTPase-activating protein nGAP isoform X8

      Conserved Domains (6) summary
      cd04013
      Location:159 → 298
      C2_SynGAP_like; C2 domain present in Ras GTPase activating protein (GAP) family
      cd05136
      Location:289 → 619
      RasGAP_DAB2IP; Ras-GTPase Activating Domain of DAB2IP and similar proteins
      smart00323
      Location:282 → 620
      RasGAP; GTPase-activator protein for Ras-like GTPases
      cd13373
      Location:36 → 173
      PH_nGAP; Neuronal growth-associated proteins Pleckstrin homology (PH) domain
      pfam12004
      Location:609 → 1087
      DUF3498; Domain of unknown function (DUF3498)
      cl02488
      Location:965 → 1104
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

    9. XM_012729038.1 → XP_012584492.1  ras GTPase-activating protein nGAP isoform X9

      Conserved Domains (6) summary
      cd04013
      Location:159 → 298
      C2_SynGAP_like; C2 domain present in Ras GTPase activating protein (GAP) family
      cd05136
      Location:289 → 619
      RasGAP_DAB2IP; Ras-GTPase Activating Domain of DAB2IP and similar proteins
      smart00323
      Location:282 → 620
      RasGAP; GTPase-activator protein for Ras-like GTPases
      cd13373
      Location:36 → 173
      PH_nGAP; Neuronal growth-associated proteins Pleckstrin homology (PH) domain
      pfam12004
      Location:609 → 1085
      DUF3498; Domain of unknown function (DUF3498)
      cl02488
      Location:963 → 1102
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

    10. XM_012729036.1 → XP_012584490.1  ras GTPase-activating protein nGAP isoform X7

      Conserved Domains (6) summary
      cd04013
      Location:190 → 329
      C2_SynGAP_like; C2 domain present in Ras GTPase activating protein (GAP) family
      cd05136
      Location:320 → 650
      RasGAP_DAB2IP; Ras-GTPase Activating Domain of DAB2IP and similar proteins
      smart00323
      Location:313 → 651
      RasGAP; GTPase-activator protein for Ras-like GTPases
      cd13373
      Location:67 → 204
      PH_nGAP; Neuronal growth-associated proteins Pleckstrin homology (PH) domain
      pfam12004
      Location:640 → 1118
      DUF3498; Domain of unknown function (DUF3498)
      cl02488
      Location:996 → 1135
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    Nucleotide Protein
    Heading Accession and Version

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