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    Ar androgen receptor [ Heterocephalus glaber (naked mole-rat) ]

    Gene ID: 101708094, updated on 8-Mar-2024

    Summary

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    Gene symbol
    Ar
    Gene description
    androgen receptor
    Locus tag
    GW7_21478
    See related
    Ensembl:ENSHGLG00000000186
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Heterocephalus glaber
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: Un
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624891.1 (3135824..3330487, complement)

    NW_004624891.1Genomic Context describing neighboring genes Neighboring gene nuclease-sensitive element-binding protein 1 pseudogene Neighboring gene endogenous retrovirus group K member 7 Pro protein-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_004624891 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Kim EB, et al. Nature, 2011 Oct 12. PMID 21993625, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables nuclear receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables steroid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in androgen receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in male gonad development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    androgen receptor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference HetGla_female_1.0 Primary Assembly

    Genomic

    1. NW_004624891.1 Reference HetGla_female_1.0 Primary Assembly

      Range
      3135824..3330487 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004871777.2 → XP_004871834.1  androgen receptor isoform X1

      UniProtKB/TrEMBL
      G5AV30
      Related
      ENSHGLP00000000173.1, ENSHGLT00000000203.1
      Conserved Domains (3) summary
      cd07073
      Location:643 → 888
      NR_LBD_AR; Ligand binding domain of the nuclear receptor androgen receptor, ligand activated transcription regulator
      cd07173
      Location:525 → 606
      NR_DBD_AR; DNA-binding domain of androgen receptor (AR) is composed of two C4-type zinc fingers
      pfam02166
      Location:6 → 433
      Androgen_recep; Androgen receptor

    2. XM_021249859.1 → XP_021105518.1  androgen receptor isoform X2

      Conserved Domains (2) summary
      cd07173
      Location:525 → 599
      NR_DBD_AR; DNA-binding domain of androgen receptor (AR) is composed of two C4-type zinc fingers
      pfam02166
      Location:6 → 433
      Androgen_recep; Androgen receptor

    3. XM_021249861.1 → XP_021105520.1  androgen receptor isoform X3

      Conserved Domains (2) summary
      pfam02166
      Location:6 → 433
      Androgen_recep; Androgen receptor
      cl02596
      Location:525 → 561
      NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers
    Nucleotide Protein
    Heading Accession and Version

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