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    LNCEGFL7OS lncRNA EGFL7 opposite strand [ Homo sapiens (human) ]

    Gene ID: 101928612, updated on 10-Dec-2024

    Summary

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    Official Symbol
    LNCEGFL7OSprovided by HGNC
    Official Full Name
    lncRNA EGFL7 opposite strandprovided by HGNC
    Primary source
    HGNC:HGNC:58066
    See related
    Ensembl:ENSG00000228401
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    HSPC324
    Expression
    Broad expression in lung (RPKM 3.3), placenta (RPKM 1.3) and 14 other tissues See more
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    Genomic context

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    See LNCEGFL7OS in Genome Data Viewer
    Location:
    9q34.3
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (136648610..136660421, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (148881592..148893402, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (139543062..139554873, complement)

    Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 1451 Neighboring gene Sharpr-MPRA regulatory region 9516 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:139524155-139524686 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29318 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:139525219-139525750 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:139525751-139526282 Neighboring gene uncharacterized LOC105376325 Neighboring gene CRISPRi-validated cis-regulatory element chr9.4291 Neighboring gene uncharacterized LOC102724193 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:139549554-139550178 Neighboring gene EGF like domain multiple 7 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:139563885-139564386 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:139564387-139564886 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:139569227-139569726 Neighboring gene microRNA 126 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:139573281-139573980 Neighboring gene 1-acylglycerol-3-phosphate O-acyltransferase 2 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:139573981-139574680 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:139576202-139577064 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:139580514-139581375 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20536

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. LncRNA HSPC324 plays role in lung development and tumorigenesis. Jafarzadeh M, et al. Genomics, 2020 May. PMID 32068121
    2. LncEGFL7OS regulates human angiogenesis by interacting with MAX at the EGFL7/miR-126 locus. Zhou Q, et al. Elife, 2019 Feb 11. PMID 30741632, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. LncRNA HSPC324 plays role in lung development and tumorigenesis.
      Title: LncRNA HSPC324 plays role in lung development and tumorigenesis.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_135132.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AF161442, BE466352
      Related
      ENST00000675837.4

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

      Range
      136648610..136660421 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060933.1 Alternate T2T-CHM13v2.0

      Range
      148881592..148893402 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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    Research Materials