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    MBD4 methyl-CpG binding domain 4, DNA glycosylase [ Rhinopithecus roxellana (golden snub-nosed monkey) ]

    Gene ID: 104676628, updated on 12-Mar-2024

    Summary

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    Gene symbol
    MBD4
    Gene description
    methyl-CpG binding domain 4, DNA glycosylase
    See related
    Ensembl:ENSRROG00000029136
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rhinopithecus roxellana
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Colobinae; Rhinopithecus
    Orthologs
    human mouse all
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    Genomic context

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    See MBD4 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    101 current ASM756505v1 (GCF_007565055.1) 1 NC_044549.1 (50226830..50240302, complement)
    100 previous assembly Rrox_v1 (GCF_000769185.1) Unplaced Scaffold NW_010824783.1 (67745..78042, complement)

    Chromosome 1 - NC_044549.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC104676625 Neighboring gene small nucleolar RNA SNORA7 Neighboring gene EF-hand calcium binding domain 12 Neighboring gene intraflagellar transport 122 Neighboring gene rhodopsin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables pyrimidine-specific mismatch base pair DNA N-glycosylase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    methyl-CpG-binding domain protein 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Rhinopithecus roxellana Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM756505v1 Primary Assembly

    Genomic

    1. NC_044549.1 Reference ASM756505v1 Primary Assembly

      Range
      50226830..50240302 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030922759.1 → XP_030778619.1  methyl-CpG-binding domain protein 4 isoform X3

      UniProtKB/TrEMBL
      A0A2K6NYN7
      Conserved Domains (2) summary
      smart00391
      Location:79 → 155
      MBD; Methyl-CpG binding domain
      cl23768
      Location:445 → 510
      ENDO3c; endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases

    2. XM_030926609.1 → XP_030782469.1  methyl-CpG-binding domain protein 4 isoform X4

      UniProtKB/TrEMBL
      A0A2K6NYN7
      Conserved Domains (2) summary
      smart00391
      Location:79 → 155
      MBD; Methyl-CpG binding domain
      cl23768
      Location:445 → 510
      ENDO3c; endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases

    3. XM_010381504.2 → XP_010379806.1  methyl-CpG-binding domain protein 4 isoform X2

      UniProtKB/TrEMBL
      A0A2K6NYN7
      Related
      ENSRROP00000009390.1
      Conserved Domains (2) summary
      smart00391
      Location:79 → 155
      MBD; Methyl-CpG binding domain
      cl23768
      Location:444 → 509
      ENDO3c; endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases

    4. XM_030926981.1 → XP_030782841.1  methyl-CpG-binding domain protein 4 isoform X5

      UniProtKB/TrEMBL
      A0A2K6NYN7
      Conserved Domains (2) summary
      smart00391
      Location:79 → 155
      MBD; Methyl-CpG binding domain
      cl23768
      Location:445 → 510
      ENDO3c; endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases

    5. XM_010381503.2 → XP_010379805.1  methyl-CpG-binding domain protein 4 isoform X1

      UniProtKB/TrEMBL
      A0A2K6NYN3, A0A2K6NYN7
      Related
      ENSRROP00000009387.1
      Conserved Domains (2) summary
      smart00391
      Location:79 → 155
      MBD; Methyl-CpG binding domain
      cl23768
      Location:445 → 510
      ENDO3c; endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases
    Nucleotide Protein
    Heading Accession and Version

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