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    TRIM46 tripartite motif containing 46 [ Cercocebus atys (sooty mangabey) ]

    Gene ID: 105593522, updated on 13-Mar-2024

    Summary

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    Gene symbol
    TRIM46
    Gene description
    tripartite motif containing 46
    See related
    Ensembl:ENSCATG00000031859
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cercocebus atys
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Cercocebus
    Orthologs
    human mouse all
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    Genomic context

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    See TRIM46 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    100 current Caty_1.0 (GCF_000955945.1) Unplaced Scaffold NW_012001518.1 (1827161..1838021)

    NW_012001518.1Genomic Context describing neighboring genes Neighboring gene non-histone chromosomal protein HMG-17 pseudogene Neighboring gene keratinocyte associated protein 2 Neighboring gene mucin 1, cell surface associated Neighboring gene thrombospondin 3 Neighboring gene metaxin 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_012001518.1 Unplaced Scaffold Reference Caty_1.0

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tripartite motif-containing protein 46

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Cercocebus atys Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Caty_1.0

    Genomic

    1. NW_012001518.1 Reference Caty_1.0

      Range
      1827161..1838021
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_012076806.1 → XP_011932196.1  tripartite motif-containing protein 46 isoform X2

      Conserved Domains (8) summary
      smart00502
      Location:257 → 382
      BBC; B-Box C-terminal domain
      cd00063
      Location:431 → 512
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      TIGR00599
      Location:9 → 83
      rad18; DNA repair protein rad18
      cd12895
      Location:519 → 728
      SPRY_PRY_TRIM46; PRY/SPRY domain in tripartite motif-containing protein 46 (TRIM46)
      cd16757
      Location:14 → 48
      RING-HC_TRIM46; RING finger, HC subclass, found in tripartite motif-containing protein 46 (TRIM46) and similar proteins
      cd19786
      Location:210 → 255
      Bbox2_TRIM46_C-I; B-box-type 2 zinc finger found in tripartite motif-containing protein 46 (TRIM46) and similar proteins
      cd19849
      Location:156 → 207
      Bbox1_TRIM46_C-I; B-box-type 1 zinc finger found in tripartite motif-containing protein 46 (TRIM46) and similar proteins
      pfam18568
      Location:360 → 409
      COS; TRIM C-terminal subgroup One Signature domain

    2. XM_012076805.1 → XP_011932195.1  tripartite motif-containing protein 46 isoform X1

      See identical proteins and their annotated locations for XP_011932195.1

      UniProtKB/TrEMBL
      A0A2K5LT50
      Related
      ENSCATP00000016117.1, ENSCATT00000040275.1
      Conserved Domains (7) summary
      smart00502
      Location:270 → 395
      BBC; B-Box C-terminal domain
      cd00063
      Location:444 → 525
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      TIGR00599
      Location:22 → 96
      rad18; DNA repair protein rad18
      cd12895
      Location:532 → 741
      SPRY_PRY_TRIM46; PRY/SPRY domain in tripartite motif-containing protein 46 (TRIM46)
      cd16757
      Location:27 → 61
      RING-HC_TRIM46; RING finger, HC subclass, found in tripartite motif-containing protein 46 (TRIM46) and similar proteins
      cd19786
      Location:223 → 268
      Bbox2_TRIM46_C-I; B-box-type 2 zinc finger found in tripartite motif-containing protein 46 (TRIM46) and similar proteins
      cd19849
      Location:169 → 220
      Bbox1_TRIM46_C-I; B-box-type 1 zinc finger found in tripartite motif-containing protein 46 (TRIM46) and similar proteins

    3. XM_012076809.1 → XP_011932199.1  tripartite motif-containing protein 46 isoform X4

      Conserved Domains (4) summary
      cd00063
      Location:369 → 450
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd00162
      Location:33 → 63
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      cd12895
      Location:457 → 666
      SPRY_PRY_TRIM46; PRY/SPRY domain in tripartite motif-containing protein 46 (TRIM46)
      cl23765
      Location:198 → 320
      iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits

    4. XM_012076811.1 → XP_011932201.1  tripartite motif-containing protein 46 isoform X5

      See identical proteins and their annotated locations for XP_011932201.1

      Conserved Domains (4) summary
      cd00063
      Location:318 → 399
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00643
      Location:96 → 137
      zf-B_box; B-box zinc finger
      cd12895
      Location:406 → 615
      SPRY_PRY_TRIM46; PRY/SPRY domain in tripartite motif-containing protein 46 (TRIM46)
      cl23765
      Location:144 → 269
      iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits

    5. XM_012076812.1 → XP_011932202.1  tripartite motif-containing protein 46 isoform X6

      Conserved Domains (4) summary
      cd00063
      Location:242 → 323
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00643
      Location:24 → 61
      zf-B_box; B-box zinc finger
      cd12895
      Location:330 → 539
      SPRY_PRY_TRIM46; PRY/SPRY domain in tripartite motif-containing protein 46 (TRIM46)
      cl23765
      Location:68 → 193
      iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits

    6. XM_012076810.1 → XP_011932200.1  tripartite motif-containing protein 46 isoform X5

      See identical proteins and their annotated locations for XP_011932200.1

      Conserved Domains (4) summary
      cd00063
      Location:318 → 399
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00643
      Location:96 → 137
      zf-B_box; B-box zinc finger
      cd12895
      Location:406 → 615
      SPRY_PRY_TRIM46; PRY/SPRY domain in tripartite motif-containing protein 46 (TRIM46)
      cl23765
      Location:144 → 269
      iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits

    7. XM_012076807.1 → XP_011932197.1  tripartite motif-containing protein 46 isoform X3

      See identical proteins and their annotated locations for XP_011932197.1

      UniProtKB/TrEMBL
      A0A2K5LT35
      Related
      ENSCATP00000016097.1, ENSCATT00000040255.1
      Conserved Domains (5) summary
      cd00063
      Location:421 → 502
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd00162
      Location:10 → 40
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      pfam00643
      Location:199 → 240
      zf-B_box; B-box zinc finger
      cd12895
      Location:509 → 718
      SPRY_PRY_TRIM46; PRY/SPRY domain in tripartite motif-containing protein 46 (TRIM46)
      cl23765
      Location:247 → 372
      iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits
    Nucleotide Protein
    Heading Accession and Version

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