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    BFAR bifunctional apoptosis regulator [ Equus asinus (ass) ]

    Gene ID: 106847165, updated on 26-Dec-2024

    Summary

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    Gene symbol
    BFAR
    Gene description
    bifunctional apoptosis regulator
    See related
    Ensembl:ENSEASG00005011391
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus asinus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    See BFAR in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_12 current EquAss-T2T_v2 (GCF_041296235.1) 14 NC_091803.1 (37744908..37777726, complement)
    101 previous assembly ASM1607732v2 (GCF_016077325.2) 14 NC_052190.1 (18823812..18860639)

    Chromosome 14 - NC_091803.1Genomic Context describing neighboring genes Neighboring gene calphotin-like Neighboring gene group 10 secretory phospholipase A2-like Neighboring gene poly(A)-specific ribonuclease Neighboring gene uncharacterized LOC139040215 Neighboring gene transfer RNA threonine (anticodon CGU)

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptomic data from 100 to 105 tissues from two female herbivores from seven species (cattle, sheep, goats, sika deer, horses, donkeys, and rabbits) and two breeds of sheep. Raw sequence reads
    • BioProject: PRJNA1017964
    • Publication: PMID 38734729
    • Analysis date: Wed Jan 08 13:44:37 2025

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    bifunctional apoptosis regulator

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_041296235.1-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquAss-T2T_v2 Primary Assembly

    Genomic

    1. NC_091803.1 Reference EquAss-T2T_v2 Primary Assembly

      Range
      37744908..37777726 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_044746607.2 → XP_044602542.2  bifunctional apoptosis regulator isoform X1

    2. XM_014866330.3 → XP_014721816.1  bifunctional apoptosis regulator isoform X3

      UniProtKB/TrEMBL
      A0A8C4M2J1, A0A8C4PMN8
      Related
      ENSEASP00005016445.2
      Conserved Domains (2) summary
      cd09513
      Location:179 → 249
      SAM_BAR; SAM domain of BAR subfamily
      cd16497
      Location:32 → 77
      RING-HC_BAR; RING finger, HC subclass, found in bifunctional apoptosis regulator (BAR)

    3. XM_014866326.3 → XP_014721812.1  bifunctional apoptosis regulator isoform X2

      UniProtKB/TrEMBL
      A0A9L0JEF9, A0A9L0JJ15
      Related
      ENSEASP00005053331.1
      Conserved Domains (3) summary
      cd09513
      Location:179 → 249
      SAM_BAR; SAM domain of BAR subfamily
      smart00454
      Location:179 → 248
      SAM; Sterile alpha motif
      cd00162
      Location:34 → 77
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

    4. XM_070484893.1 → XP_070340994.1  bifunctional apoptosis regulator isoform X3

    5. XM_044746608.2 → XP_044602543.2  bifunctional apoptosis regulator isoform X1

    6. XM_070484892.1 → XP_070340993.1  bifunctional apoptosis regulator isoform X1

    7. XM_070484894.1 → XP_070340995.1  bifunctional apoptosis regulator isoform X3

    8. XM_044746611.2 → XP_044602546.2  bifunctional apoptosis regulator isoform X1

    RNA

    1. XR_001402077.3 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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