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    grb7.L growth factor receptor bound protein 7 L homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 108700772, updated on 27-Dec-2024

    Summary

    Official Symbol
    grb7.L
    Official Full Name
    growth factor receptor bound protein 7 L homeolog
    Primary source
    Xenbase:XB-GENE-17332903
    Locus tag
    XELAEV_18043160mg
    See related
    EnsemblRapid:ENSXLAG00005026959 AllianceGenome:Xenbase:XB-GENE-17332903
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Summary
    Predicted to act upstream of or within signal transduction. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in esophagus adenocarcinoma. Orthologous to human GRB7 (growth factor receptor bound protein 7). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See grb7.L in Genome Data Viewer
    Location:
    chromosome: 9_10L
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10L NC_054387.1 (2154881..2183440, complement)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10L NC_030740.1 (2118599..2142030, complement)

    Chromosome 9_10L - NC_054387.1Genomic Context describing neighboring genes Neighboring gene IKAROS family zinc finger 3 L homeolog Neighboring gene retinol dehydrogenase 8-like Neighboring gene nuclear factor 7, ovary Neighboring gene E3 ubiquitin-protein ligase TRIM39-like

    Genomic regions, transcripts, and products

    General protein information

    Preferred Names
    growth factor receptor-bound protein 7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054387.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      2154881..2183440 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_041576136.1XP_041432070.1  growth factor receptor-bound protein 7 isoform X1

      UniProtKB/TrEMBL
      A0A8J1LTM3
      Related
      ENSXLAP00005080278.1, ENSXLAT00005081871.1
      Conserved Domains (3) summary
      cd10413
      Location:508615
      SH2_Grb7; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 7 (Grb7) proteins
      cd01259
      Location:309431
      PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
      cd16140
      Location:184271
      RA_GRB7; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 7
    2. XM_018234707.2XP_018090196.1  growth factor receptor-bound protein 7 isoform X2

      UniProtKB/TrEMBL
      A0A1L8ERV9, A0A974BWK5
      Related
      ENSXLAP00005080413.1, ENSXLAT00005082007.1