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    OCRL OCRL inositol polyphosphate-5-phosphatase [ Lonchura striata (white-rumped munia) ]

    Gene ID: 110480100, updated on 2-Oct-2024

    Summary

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    Gene symbol
    OCRL
    Gene description
    OCRL inositol polyphosphate-5-phosphatase
    Locus tag
    RLOC_00014679
    See related
    Ensembl:ENSLSDG00000001725
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Lonchura striata
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves; Passeriformes; Passeroidea; Estrildidae; Estrildinae; Lonchura
    Orthologs
    human mouse all
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    Genomic context

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    See OCRL in Genome Data Viewer
    Location:
    chromosome: 4A
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    RS_2024_09 current lonStrDom2 (GCF_005870125.1) 4A NC_042570.1 (15360972..15382876)

    Chromosome 4A - NC_042570.1Genomic Context describing neighboring genes Neighboring gene peptidylprolyl cis/trans isomerase, NIMA-interacting 4 Neighboring gene ERCC excision repair 6 like, spindle assembly checkpoint helicase Neighboring gene X-prolyl aminopeptidase 2 Neighboring gene SAM and SH3 domain containing 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_042570.1 Chromosome 4A Reference lonStrDom2 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables inositol phosphate phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in phosphatidylinositol dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    inositol polyphosphate 5-phosphatase OCRL
    Names
    Inositol polyphosphate 5-phosphatase OCRL-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_005870125.1-RS_2024_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference lonStrDom2 Primary Assembly

    Genomic

    1. NC_042570.1 Reference lonStrDom2 Primary Assembly

      Range
      15360972..15382876
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021547805.1 → XP_021403480.1  inositol polyphosphate 5-phosphatase OCRL isoform X2

      UniProtKB/TrEMBL
      A0A218V3R4
      Conserved Domains (3) summary
      cd09093
      Location:235 → 529
      INPP5c_INPP5B; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins
      cd04380
      Location:664 → 895
      RhoGAP_OCRL1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in OCRL1-like proteins. OCRL1 (oculocerebrorenal syndrome of Lowe 1)-like proteins contain two conserved domains: a central inositol polyphosphate 5-phosphatase domain and ...
      pfam16726
      Location:17 → 115
      OCRL_clath_bd; Inositol polyphosphate 5-phosphatase clathrin binding domain

    2. XM_021547803.2 → XP_021403478.1  inositol polyphosphate 5-phosphatase OCRL isoform X1

      UniProtKB/TrEMBL
      A0A218V3R4
      Related
      ENSLSDP00000002168.1
      Conserved Domains (3) summary
      cd09093
      Location:236 → 530
      INPP5c_INPP5B; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins
      cd04380
      Location:665 → 896
      RhoGAP_OCRL1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in OCRL1-like proteins. OCRL1 (oculocerebrorenal syndrome of Lowe 1)-like proteins contain two conserved domains: a central inositol polyphosphate 5-phosphatase domain and ...
      pfam16726
      Location:17 → 116
      OCRL_clath_bd; Inositol polyphosphate 5-phosphatase clathrin binding domain
    Nucleotide Protein
    Heading Accession and Version

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