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    dsh Segment polarity protein dishevelled [ Centruroides sculpturatus (bark scorpion) ]

    Gene ID: 111612719, updated on 3-Jul-2024

    Summary

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    Gene symbol
    dsh
    Gene description
    Segment polarity protein dishevelled
    See related
    EnsemblRapid:LOC111612719
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Centruroides sculpturatus
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Scorpiones; Buthida; Buthoidea; Buthidae; Centruroides
    Orthologs
    fruit fly all
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    Genomic context

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    See dsh in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    100 current Cexi_2.0 (GCF_000671375.1) Unplaced Scaffold NW_019385941.1 (61392..89906)

    NW_019385941.1Genomic Context describing neighboring genes Neighboring gene probable serine hydrolase Neighboring gene uncharacterized LOC111612721 Neighboring gene E3 ubiquitin-protein ligase MIB2-like Neighboring gene DIS3-like exonuclease 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_019385941 Unplaced Scaffold Reference Cexi_2.0

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables frizzled binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in canonical Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    segment polarity protein dishevelled homolog DVL-3-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Centruroides sculpturatus Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Cexi_2.0

    Genomic

    1. NW_019385941.1 Reference Cexi_2.0

      Range
      61392..89906
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023353958.1 → XP_023209726.1  segment polarity protein dishevelled homolog DVL-3-like isoform X1

      Related
      XP_023209726.1, XM_023353958.1
      Conserved Domains (5) summary
      smart00021
      Location:3 → 84
      DAX; Domain present in Dishevelled and axin
      cd00992
      Location:284 → 371
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd04438
      Location:458 → 540
      DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
      pfam02377
      Location:90 → 282
      Dishevelled; Dishevelled specific domain
      pfam12316
      Location:544 → 703
      Dsh_C; Segment polarity protein dishevelled (Dsh) C terminal

    2. XM_023353959.1 → XP_023209727.1  segment polarity protein dishevelled homolog DVL-3-like isoform X2

      Related
      XP_023209727.1, XM_023353959.1
      Conserved Domains (5) summary
      smart00021
      Location:3 → 84
      DAX; Domain present in Dishevelled and axin
      cd00992
      Location:284 → 371
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd04438
      Location:451 → 533
      DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
      pfam02377
      Location:90 → 282
      Dishevelled; Dishevelled specific domain
      pfam12316
      Location:537 → 696
      Dsh_C; Segment polarity protein dishevelled (Dsh) C terminal

    3. XM_023353960.1 → XP_023209728.1  segment polarity protein dishevelled homolog DVL-3-like isoform X3

      Related
      XP_023209728.1, XM_023353960.1
      Conserved Domains (4) summary
      smart00021
      Location:3 → 84
      DAX; Domain present in Dishevelled and axin
      cd00992
      Location:284 → 371
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd04438
      Location:451 → 533
      DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
      pfam02377
      Location:90 → 282
      Dishevelled; Dishevelled specific domain
    Nucleotide Protein
    Heading Accession and Version

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