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    Trim37 tripartite motif containing 37 [ Urocitellus parryii (Arctic ground squirrel) ]

    Gene ID: 113195691, updated on 15-Mar-2024

    Summary

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    Gene symbol
    Trim37
    Gene description
    tripartite motif containing 37
    See related
    Ensembl:ENSUPAG00010013575
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Urocitellus parryii
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae; Xerinae; Marmotini; Urocitellus
    Orthologs
    human mouse all
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    Genomic context

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    See Trim37 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    100 current ASM342692v1 (GCF_003426925.1) Unplaced Scaffold NW_020540246.1 (165887..352125)

    NW_020540246.1Genomic Context describing neighboring genes Neighboring gene proline rich 11 Neighboring gene spindle and kinetochore associated complex subunit 2 Neighboring gene U6 spliceosomal RNA Neighboring gene 60S ribosomal protein L7 pseudogene Neighboring gene protein phosphatase, Mg2+/Mn2+ dependent 1E Neighboring gene protein KTI12 homolog Neighboring gene immediate early response 3-interacting protein 1 pseudogene Neighboring gene U6atac minor spliceosomal RNA Neighboring gene RAD51 paralog C

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_020540246 Unplaced Scaffold Reference ASM342692v1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables tumor necrosis factor receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of NF-kappaB transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of centriole replication IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of NF-kappaB transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein autoubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in aggresome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in peroxisome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase TRIM37

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Urocitellus parryii Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM342692v1

    Genomic

    1. NW_020540246.1 Reference ASM342692v1

      Range
      165887..352125
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_026407312.1 → XP_026263097.1  E3 ubiquitin-protein ligase TRIM37 isoform X1

      UniProtKB/TrEMBL
      A0A8D2KJ80
      Conserved Domains (4) summary
      smart00502
      Location:132 → 254
      BBC; B-Box C-terminal domain
      smart00336
      Location:91 → 132
      BBOX; B-Box-type zinc finger
      cd03773
      Location:273 → 406
      MATH_TRIM37; Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins. ...
      cd16619
      Location:13 → 55
      mRING-HC-C4C4_TRIM37_C-VIII; Modified RING finger, HC subclass (C4C4-type), found in tripartite motif-containing protein 37 (TRIM37) and similar proteins

    2. XM_026407311.1 → XP_026263096.1  E3 ubiquitin-protein ligase TRIM37 isoform X1

      UniProtKB/TrEMBL
      A0A8D2KJ80
      Conserved Domains (4) summary
      smart00502
      Location:132 → 254
      BBC; B-Box C-terminal domain
      smart00336
      Location:91 → 132
      BBOX; B-Box-type zinc finger
      cd03773
      Location:273 → 406
      MATH_TRIM37; Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins. ...
      cd16619
      Location:13 → 55
      mRING-HC-C4C4_TRIM37_C-VIII; Modified RING finger, HC subclass (C4C4-type), found in tripartite motif-containing protein 37 (TRIM37) and similar proteins

    3. XM_026407315.1 → XP_026263100.1  E3 ubiquitin-protein ligase TRIM37 isoform X4

      UniProtKB/TrEMBL
      A0A8D2HQ73, A0A8D2KJ80
      Related
      ENSUPAP00010017021.1, ENSUPAT00010019407.1
      Conserved Domains (4) summary
      smart00502
      Location:132 → 254
      BBC; B-Box C-terminal domain
      smart00336
      Location:91 → 132
      BBOX; B-Box-type zinc finger
      cd03773
      Location:273 → 406
      MATH_TRIM37; Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins. ...
      cd16619
      Location:13 → 55
      mRING-HC-C4C4_TRIM37_C-VIII; Modified RING finger, HC subclass (C4C4-type), found in tripartite motif-containing protein 37 (TRIM37) and similar proteins

    4. XM_026407313.1 → XP_026263098.1  E3 ubiquitin-protein ligase TRIM37 isoform X2

      UniProtKB/TrEMBL
      A0A8D2KJ80
      Conserved Domains (4) summary
      smart00502
      Location:132 → 254
      BBC; B-Box C-terminal domain
      smart00336
      Location:91 → 132
      BBOX; B-Box-type zinc finger
      cd03773
      Location:273 → 406
      MATH_TRIM37; Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins. ...
      cd16619
      Location:13 → 55
      mRING-HC-C4C4_TRIM37_C-VIII; Modified RING finger, HC subclass (C4C4-type), found in tripartite motif-containing protein 37 (TRIM37) and similar proteins

    5. XM_026407316.1 → XP_026263101.1  E3 ubiquitin-protein ligase TRIM37 isoform X5

      UniProtKB/TrEMBL
      A0A8D2KJ80
      Conserved Domains (4) summary
      cd00021
      Location:93 → 121
      BBOX; B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction.
      cd03773
      Location:232 → 365
      MATH_TRIM37; Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins. ...
      cd16619
      Location:13 → 55
      mRING-HC-C4C4_TRIM37_C-VIII; Modified RING finger, HC subclass (C4C4-type), found in tripartite motif-containing protein 37 (TRIM37) and similar proteins
      cl25407
      Location:124 → 213
      ClassIIa_HDAC_Gln-rich-N; Glutamine-rich N-terminal helical domain of various Class IIa histone deacetylases (HDAC4, HDAC5 and HDCA9)

    6. XM_026407314.1 → XP_026263099.1  E3 ubiquitin-protein ligase TRIM37 isoform X3

      UniProtKB/TrEMBL
      A0A8D2KJ80
      Conserved Domains (4) summary
      smart00502
      Location:114 → 236
      BBC; B-Box C-terminal domain
      smart00336
      Location:73 → 114
      BBOX; B-Box-type zinc finger
      cd03773
      Location:255 → 388
      MATH_TRIM37; Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins. ...
      cd16619
      Location:1 → 37
      mRING-HC-C4C4_TRIM37_C-VIII; Modified RING finger, HC subclass (C4C4-type), found in tripartite motif-containing protein 37 (TRIM37) and similar proteins

    7. XM_026407317.1 → XP_026263102.1  E3 ubiquitin-protein ligase TRIM37 isoform X6

      UniProtKB/TrEMBL
      A0A8D2KJ80
      Related
      ENSUPAP00010017069.1, ENSUPAT00010019459.1
      Conserved Domains (3) summary
      smart00502
      Location:117 → 239
      BBC; B-Box C-terminal domain
      smart00336
      Location:76 → 117
      BBOX; B-Box-type zinc finger
      cd03773
      Location:258 → 391
      MATH_TRIM37; Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins. ...
    Nucleotide Protein
    Heading Accession and Version

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