U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    PTEN phosphatase and tensin homolog [ Phyllostomus discolor (pale spear-nosed bat) ]

    Gene ID: 114497080, updated on 30-Mar-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    PTEN
    Gene description
    phosphatase and tensin homolog
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Phyllostomus discolor
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Phyllostomidae; Phyllostominae; Phyllostomus
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See PTEN in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    101 current mPhyDis1.pri.v3 (GCF_004126475.2) 5 NC_040907.2 (142877686..142963646)
    100 previous assembly mPhyDis1_v1.p (GCF_004126475.1) 5 NC_040907.1 (134673514..134757231, complement)

    Chromosome 5 - NC_040907.2Genomic Context describing neighboring genes Neighboring gene high mobility group protein B2-like Neighboring gene uncharacterized LOC118500850 Neighboring gene killin, p53 regulated DNA replication inhibitor Neighboring gene uncharacterized LOC118500851 Neighboring gene U2 spliceosomal RNA Neighboring gene renalase, FAD dependent amine oxidase

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell motility IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of cell population proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Phyllostomus discolor Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mPhyDis1.pri.v3

    Genomic

    1. NC_040907.2 Reference mPhyDis1.pri.v3

      Range
      142877686..142963646
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028512714.2 → XP_028368515.1  phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

      UniProtKB/TrEMBL
      A0A6J2LRJ7
      Conserved Domains (3) summary
      PRK12323
      Location:177 → 279
      PRK12323; DNA polymerase III subunits gamma and tau; Provisional
      pfam10409
      Location:484 → 644
      PTEN_C2; C2 domain of PTEN tumor-suppressor protein
      cd14509
      Location:320 → 477
      PTP_PTEN; protein tyrosine phosphatase-like catalytic domain of phosphatase and tensin homolog
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.