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    LIFR LIF receptor subunit alpha [ Phoca vitulina (harbor seal) ]

    Gene ID: 116639033, updated on 18-Mar-2024

    Summary

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    Gene symbol
    LIFR
    Gene description
    LIF receptor subunit alpha
    See related
    EnsemblRapid:ENSPVHG00000018421
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Phoca vitulina
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae; Phoca
    Orthologs
    human mouse all
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    Genomic context

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    See LIFR in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    100 current GSC_HSeal_1.0 (GCF_004348235.1) Unplaced Scaffold NW_022589720.1 (30017720..30072806, complement)

    NW_022589720.1Genomic Context describing neighboring genes Neighboring gene glial cell derived neurotrophic factor Neighboring gene EGF like, fibronectin type III and laminin G domains Neighboring gene U2 spliceosomal RNA Neighboring gene nucleophosmin-like Neighboring gene uncharacterized LOC116639025 Neighboring gene oncostatin M receptor

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_022589720 Unplaced Scaffold Reference GSC_HSeal_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ciliary neurotrophic factor receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cytokine binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables leukemia inhibitory factor receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables oncostatin-M receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytokine-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of cell population proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    LOW QUALITY PROTEIN: leukemia inhibitory factor receptor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Phoca vitulina Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GSC_HSeal_1.0 Primary Assembly

    Genomic

    1. NW_022589720.1 Reference GSC_HSeal_1.0 Primary Assembly

      Range
      30017720..30072806 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_032415163.1 → XP_032271054.1  LOW QUALITY PROTEIN: leukemia inhibitory factor receptor

      Related
      ENSPVHP00000023195.1, ENSPVHT00000026044.1
      Conserved Domains (4) summary
      cd00063
      Location:433 → 530
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam17971
      Location:131 → 244
      LIFR_D2; Leukemia inhibitory factor receptor D2 domain
      pfam18207
      Location:55 → 129
      LIFR_N; Leukemia inhibitory factor receptor N-terminal domain
      cl21522
      Location:552 → 619
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    Nucleotide Protein
    Heading Accession and Version

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