Baz2a bromodomain adjacent to zinc finger domain, 2A [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Baz2aprovided by MGI
Official Full Name: bromodomain adjacent to zinc finger domain, 2Aprovided by MGI
Primary source: MGI:MGI:2151152
See related: Ensembl:ENSMUSG00000040054 AllianceGenome:MGI:2151152
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Tip5; Walp3; mKIAA0314; C030005G16Rik
Summary: Enables chromatin-protein adaptor activity; lysine-acetylated histone binding activity; and nucleic acid binding activity. Involved in DNA methylation-dependent heterochromatin formation; negative regulation of transcription by RNA polymerase I; and rDNA heterochromatin formation. Acts upstream of or within chromatin remodeling. Located in nucleolus and rDNA heterochromatin. Part of NoRC complex and chromatin silencing complex. Is expressed in several structures, including central nervous system; early conceptus; eye; genitourinary system; and paraxial mesenchyme. Orthologous to human BAZ2A (bromodomain adjacent to zinc finger domain 2A). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Ubiquitous expression in thymus adult (RPKM 35.9), testis adult (RPKM 35.5) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 10 D3; 10 76.4 cM

Exon count:: 33

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	10	NC_000076.7 (127927453..127965172)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	10	NC_000076.6 (128091370..128129303)

Chromosome 10 - NC_000076.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

In vivo CRISPR screening identifies BAZ2 chromatin remodelers as druggable regulators of mammalian liver regeneration.
Title: In vivo CRISPR screening identifies BAZ2 chromatin remodelers as druggable regulators of mammalian liver regeneration.
BAZ2A safeguards genome architecture of ground-state pluripotent stem cells.
Title: BAZ2A safeguards genome architecture of ground-state pluripotent stem cells.
TIP5 is critical for the initiation of prostate cancer of luminal origin mediated by Pten-loss whereas it is dispensable once Pten-loss mediated transformation is established.
Title: TIP5 primes prostate luminal cells for the oncogenic transformation mediated by PTEN-loss.
NuRD negatively regulates TIP5 expression, thereby inhibiting ribosomal DNA (rDNA) methylation and maintaining demethylation state of rDNA promoters.
Title: CHD4/NuRD maintains demethylation state of rDNA promoters through inhibiting the expression of the rDNA methyltransferase recruiter TIP5.
Tip5 not only mediates the establishment of rDNA silencing but also the formation of perinucleolar heterochromatin that contains centric and pericentric repeats.
Title: The NoRC complex mediates the heterochromatin formation and stability of silent rRNA genes and centromeric repeats.
Data show that MOF acetylates TIP5, the largest subunit of NoRC, at a single lysine residue, K633, adjacent to the TIP5 RNA-binding domain, and that SIRT1 (removes the acetyl group from K633.
Title: Reversible acetylation of the chromatin remodelling complex NoRC is required for non-coding RNA-dependent silencing.
Mutations that disrupt the stem-loop structure impair binding of TIP5, the large subunit of NoRC, to pRNA and abolish targeting of NoRC to nucleoli.
Title: The structure of NoRC-associated RNA is crucial for targeting the chromatin remodelling complex NoRC to the nucleolus.
Overexpression of TIP5, the large subunit of NoRC, mediates deacetylation of nucleosomes near the rDNA promoter. TIP5 associates with HDAC1 in vivo & in vitro. Deletion of the C-terminal PHD finger & bromodomain abolishes the interaction of TIP5 & HDAC1.
Title: The chromatin remodeling complex NoRC targets HDAC1 to the ribosomal gene promoter and represses RNA polymerase I transcription.
The PHD finger/bromodomain of NoRC interacts with acetylated histone H4K16 and is sufficient for rDNA silencing.
Title: The PHD finger/bromodomain of NoRC interacts with acetylated histone H4K16 and is sufficient for rDNA silencing.

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (6)
Targeted (2) 1 citation

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

NoName (e-PCR)
- UniSTS:224552

C76435 (e-PCR)
- UniSTS:160045

RH124269 (e-PCR)
- UniSTS:161091

RH136261 (e-PCR)
- UniSTS:210254

RH125974 (e-PCR)
- UniSTS:162686

RH139248 (e-PCR)
- UniSTS:221334

RH69868 (e-PCR)
- UniSTS:15021

RH126360 (e-PCR)
- UniSTS:163068

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables RNA binding	IDA Inferred from Direct Assay more info	PubMed
enables chromatin-protein adaptor activity	IDA Inferred from Direct Assay more info	PubMed
enables histone binding	ISO Inferred from Sequence Orthology more info
enables lysine-acetylated histone binding	IDA Inferred from Direct Assay more info	PubMed
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in DNA methylation-dependent constitutive heterochromatin formation	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within chromatin remodeling	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within heterochromatin formation	IDA Inferred from Direct Assay more info	PubMed
involved_in heterochromatin formation	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within heterochromatin formation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of transcription by RNA polymerase I	IDA Inferred from Direct Assay more info	PubMed
involved_in negative regulation of transcription by RNA polymerase I	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within rDNA heterochromatin formation	IDA Inferred from Direct Assay more info	PubMed
involved_in rDNA heterochromatin formation	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within rDNA heterochromatin formation	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of NoRC complex	IPI Inferred from Physical Interaction more info	PubMed
part_of chromatin silencing complex	IDA Inferred from Direct Assay more info	PubMed
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in nuclear speck	ISO Inferred from Sequence Orthology more info
located_in nucleolus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleolus	NAS Non-traceable Author Statement more info	PubMed
located_in nucleoplasm	TAS Traceable Author Statement more info
located_in nucleus	ISO Inferred from Sequence Orthology more info
located_in rDNA heterochromatin	IBA Inferred from Biological aspect of Ancestor more info
located_in rDNA heterochromatin	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: bromodomain adjacent to zinc finger domain protein 2A

Names: TTF-I-interacting protein 5; transcription termination factor I-interacting protein 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_054078.2 → NP_473419.2 bromodomain adjacent to zinc finger domain protein 2A

See identical proteins and their annotated locations for NP_473419.2

Status: VALIDATED

Source sequence(s)

AC131120, AC166817

Consensus CDS

CCDS36088.1

UniProtKB/TrEMBL

A0A5F8MPQ7, F8VPM0

Related

ENSMUSP00000044359.9, ENSMUST00000045621.9

Conserved Domains (8) summary

cd05503
Location:1780 → 1876

Bromo_BAZ2A_B_like; Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting ...

smart00571
Location:839 → 901

DDT; domain in different transcription and chromosome remodeling factors

PHA03307
Location:269 → 516

PHA03307; transcriptional regulator ICP4; Provisional

PRK07003
Location:407 → 533

PRK07003; DNA polymerase III subunit gamma/tau

cd01397
Location:541 → 613

HAT_MBD; Methyl-CpG binding domains (MBD) present in putative chromatin remodelling factor such as BAZ2A; BAZ2A contains a MBD, DDT, PHD-type zinc finger and Bromo domain suggesting that BAZ2A might be associated with histone acetyltransferase (HAT) activity. The ...

cd15629
Location:1662 → 1708

PHD_BAZ2A; PHD finger found in bromodomain adjacent to zinc finger domain protein 2A (BAZ2A)

pfam03154
Location:1150 → 1420

Atrophin-1; Atrophin-1 family

pfam15613
Location:1423 → 1457

WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000076.7 Reference GRCm39 C57BL/6J

Range

127927453..127965172

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_011243278.4 → XP_011241580.1 bromodomain adjacent to zinc finger domain protein 2A isoform X1

See identical proteins and their annotated locations for XP_011241580.1

UniProtKB/TrEMBL

A0A1W2P6X9, E9Q374

Conserved Domains (8) summary

cd05503
Location:1781 → 1877

Bromo_BAZ2A_B_like; Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting ...

smart00571
Location:840 → 902

DDT; domain in different transcription and chromosome remodeling factors

PHA03307
Location:269 → 517

PHA03307; transcriptional regulator ICP4; Provisional

PRK07003
Location:408 → 534

PRK07003; DNA polymerase III subunit gamma/tau

cd01397
Location:542 → 614

HAT_MBD; Methyl-CpG binding domains (MBD) present in putative chromatin remodelling factor such as BAZ2A; BAZ2A contains a MBD, DDT, PHD-type zinc finger and Bromo domain suggesting that BAZ2A might be associated with histone acetyltransferase (HAT) activity. The ...

cd15629
Location:1663 → 1709

PHD_BAZ2A; PHD finger found in bromodomain adjacent to zinc finger domain protein 2A (BAZ2A)

pfam03154
Location:1151 → 1421

Atrophin-1; Atrophin-1 family

pfam15613
Location:1424 → 1458

WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
XM_030244833.2 → XP_030100693.1 bromodomain adjacent to zinc finger domain protein 2A isoform X2

UniProtKB/TrEMBL

A0A5F8MPQ7, F8VPM0

Conserved Domains (8) summary

cd05503
Location:1780 → 1876

Bromo_BAZ2A_B_like; Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting ...

smart00571
Location:839 → 901

DDT; domain in different transcription and chromosome remodeling factors

PHA03307
Location:269 → 516

PHA03307; transcriptional regulator ICP4; Provisional

PRK07003
Location:407 → 533

PRK07003; DNA polymerase III subunit gamma/tau

cd01397
Location:541 → 613

HAT_MBD; Methyl-CpG binding domains (MBD) present in putative chromatin remodelling factor such as BAZ2A; BAZ2A contains a MBD, DDT, PHD-type zinc finger and Bromo domain suggesting that BAZ2A might be associated with histone acetyltransferase (HAT) activity. The ...

cd15629
Location:1662 → 1708

PHD_BAZ2A; PHD finger found in bromodomain adjacent to zinc finger domain protein 2A (BAZ2A)

pfam03154
Location:1150 → 1420

Atrophin-1; Atrophin-1 family

pfam15613
Location:1423 → 1457

WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
XM_011243283.4 → XP_011241585.1 bromodomain adjacent to zinc finger domain protein 2A isoform X1

See identical proteins and their annotated locations for XP_011241585.1

UniProtKB/TrEMBL

A0A1W2P6X9, E9Q374

Conserved Domains (8) summary

cd05503
Location:1781 → 1877

Bromo_BAZ2A_B_like; Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting ...

smart00571
Location:840 → 902

DDT; domain in different transcription and chromosome remodeling factors

PHA03307
Location:269 → 517

PHA03307; transcriptional regulator ICP4; Provisional

PRK07003
Location:408 → 534

PRK07003; DNA polymerase III subunit gamma/tau

cd01397
Location:542 → 614

HAT_MBD; Methyl-CpG binding domains (MBD) present in putative chromatin remodelling factor such as BAZ2A; BAZ2A contains a MBD, DDT, PHD-type zinc finger and Bromo domain suggesting that BAZ2A might be associated with histone acetyltransferase (HAT) activity. The ...

cd15629
Location:1663 → 1709

PHD_BAZ2A; PHD finger found in bromodomain adjacent to zinc finger domain protein 2A (BAZ2A)

pfam03154
Location:1151 → 1421

Atrophin-1; Atrophin-1 family

pfam15613
Location:1424 → 1458

WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
XM_011243285.4 → XP_011241587.1 bromodomain adjacent to zinc finger domain protein 2A isoform X2

See identical proteins and their annotated locations for XP_011241587.1

UniProtKB/TrEMBL

A0A5F8MPQ7, F8VPM0

Conserved Domains (8) summary

cd05503
Location:1780 → 1876

Bromo_BAZ2A_B_like; Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting ...

smart00571
Location:839 → 901

DDT; domain in different transcription and chromosome remodeling factors

PHA03307
Location:269 → 516

PHA03307; transcriptional regulator ICP4; Provisional

PRK07003
Location:407 → 533

PRK07003; DNA polymerase III subunit gamma/tau

cd01397
Location:541 → 613

HAT_MBD; Methyl-CpG binding domains (MBD) present in putative chromatin remodelling factor such as BAZ2A; BAZ2A contains a MBD, DDT, PHD-type zinc finger and Bromo domain suggesting that BAZ2A might be associated with histone acetyltransferase (HAT) activity. The ...

cd15629
Location:1662 → 1708

PHD_BAZ2A; PHD finger found in bromodomain adjacent to zinc finger domain protein 2A (BAZ2A)

pfam03154
Location:1150 → 1420

Atrophin-1; Atrophin-1 family

pfam15613
Location:1423 → 1457

WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
XM_036155519.1 → XP_036011412.1 bromodomain adjacent to zinc finger domain protein 2A isoform X4

UniProtKB/TrEMBL

A0A5F8MPQ7
XM_011243280.4 → XP_011241582.1 bromodomain adjacent to zinc finger domain protein 2A isoform X1

See identical proteins and their annotated locations for XP_011241582.1

UniProtKB/TrEMBL

A0A1W2P6X9, E9Q374

Conserved Domains (8) summary

cd05503
Location:1781 → 1877

Bromo_BAZ2A_B_like; Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting ...

smart00571
Location:840 → 902

DDT; domain in different transcription and chromosome remodeling factors

PHA03307
Location:269 → 517

PHA03307; transcriptional regulator ICP4; Provisional

PRK07003
Location:408 → 534

PRK07003; DNA polymerase III subunit gamma/tau

cd01397
Location:542 → 614

HAT_MBD; Methyl-CpG binding domains (MBD) present in putative chromatin remodelling factor such as BAZ2A; BAZ2A contains a MBD, DDT, PHD-type zinc finger and Bromo domain suggesting that BAZ2A might be associated with histone acetyltransferase (HAT) activity. The ...

cd15629
Location:1663 → 1709

PHD_BAZ2A; PHD finger found in bromodomain adjacent to zinc finger domain protein 2A (BAZ2A)

pfam03154
Location:1151 → 1421

Atrophin-1; Atrophin-1 family

pfam15613
Location:1424 → 1458

WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
XM_030244832.2 → XP_030100692.1 bromodomain adjacent to zinc finger domain protein 2A isoform X1

UniProtKB/TrEMBL

A0A1W2P6X9, E9Q374

Conserved Domains (8) summary

cd05503
Location:1781 → 1877

Bromo_BAZ2A_B_like; Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting ...

smart00571
Location:840 → 902

DDT; domain in different transcription and chromosome remodeling factors

PHA03307
Location:269 → 517

PHA03307; transcriptional regulator ICP4; Provisional

PRK07003
Location:408 → 534

PRK07003; DNA polymerase III subunit gamma/tau

cd01397
Location:542 → 614

HAT_MBD; Methyl-CpG binding domains (MBD) present in putative chromatin remodelling factor such as BAZ2A; BAZ2A contains a MBD, DDT, PHD-type zinc finger and Bromo domain suggesting that BAZ2A might be associated with histone acetyltransferase (HAT) activity. The ...

cd15629
Location:1663 → 1709

PHD_BAZ2A; PHD finger found in bromodomain adjacent to zinc finger domain protein 2A (BAZ2A)

pfam03154
Location:1151 → 1421

Atrophin-1; Atrophin-1 family

pfam15613
Location:1424 → 1458

WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
XM_011243282.4 → XP_011241584.1 bromodomain adjacent to zinc finger domain protein 2A isoform X1

See identical proteins and their annotated locations for XP_011241584.1

UniProtKB/TrEMBL

A0A1W2P6X9, E9Q374

Conserved Domains (8) summary

cd05503
Location:1781 → 1877

Bromo_BAZ2A_B_like; Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting ...

smart00571
Location:840 → 902

DDT; domain in different transcription and chromosome remodeling factors

PHA03307
Location:269 → 517

PHA03307; transcriptional regulator ICP4; Provisional

PRK07003
Location:408 → 534

PRK07003; DNA polymerase III subunit gamma/tau

cd01397
Location:542 → 614

HAT_MBD; Methyl-CpG binding domains (MBD) present in putative chromatin remodelling factor such as BAZ2A; BAZ2A contains a MBD, DDT, PHD-type zinc finger and Bromo domain suggesting that BAZ2A might be associated with histone acetyltransferase (HAT) activity. The ...

cd15629
Location:1663 → 1709

PHD_BAZ2A; PHD finger found in bromodomain adjacent to zinc finger domain protein 2A (BAZ2A)

pfam03154
Location:1151 → 1421

Atrophin-1; Atrophin-1 family

pfam15613
Location:1424 → 1458

WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
XM_030244830.1 → XP_030100690.1 bromodomain adjacent to zinc finger domain protein 2A isoform X1

UniProtKB/TrEMBL

A0A1W2P6X9, E9Q374

Conserved Domains (8) summary

cd05503
Location:1781 → 1877

Bromo_BAZ2A_B_like; Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting ...

smart00571
Location:840 → 902

DDT; domain in different transcription and chromosome remodeling factors

PHA03307
Location:269 → 517

PHA03307; transcriptional regulator ICP4; Provisional

PRK07003
Location:408 → 534

PRK07003; DNA polymerase III subunit gamma/tau

cd01397
Location:542 → 614

HAT_MBD; Methyl-CpG binding domains (MBD) present in putative chromatin remodelling factor such as BAZ2A; BAZ2A contains a MBD, DDT, PHD-type zinc finger and Bromo domain suggesting that BAZ2A might be associated with histone acetyltransferase (HAT) activity. The ...

cd15629
Location:1663 → 1709

PHD_BAZ2A; PHD finger found in bromodomain adjacent to zinc finger domain protein 2A (BAZ2A)

pfam03154
Location:1151 → 1421

Atrophin-1; Atrophin-1 family

pfam15613
Location:1424 → 1458

WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
XM_006513115.4 → XP_006513178.1 bromodomain adjacent to zinc finger domain protein 2A isoform X3

UniProtKB/TrEMBL

A0A1W2P6X9

Conserved Domains (8) summary

cd05503
Location:1780 → 1876

Bromo_BAZ2A_B_like; Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting ...

smart00571
Location:840 → 902

DDT; domain in different transcription and chromosome remodeling factors

PHA03307
Location:269 → 517

PHA03307; transcriptional regulator ICP4; Provisional

PRK07003
Location:408 → 534

PRK07003; DNA polymerase III subunit gamma/tau

cd01397
Location:542 → 614

HAT_MBD; Methyl-CpG binding domains (MBD) present in putative chromatin remodelling factor such as BAZ2A; BAZ2A contains a MBD, DDT, PHD-type zinc finger and Bromo domain suggesting that BAZ2A might be associated with histone acetyltransferase (HAT) activity. The ...

cd15629
Location:1663 → 1709

PHD_BAZ2A; PHD finger found in bromodomain adjacent to zinc finger domain protein 2A (BAZ2A)

pfam03154
Location:1151 → 1421

Atrophin-1; Atrophin-1 family

pfam15613
Location:1424 → 1458

WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
XM_006513114.4 → XP_006513177.1 bromodomain adjacent to zinc finger domain protein 2A isoform X2

See identical proteins and their annotated locations for XP_006513177.1

UniProtKB/TrEMBL

A0A5F8MPQ7, F8VPM0

Conserved Domains (8) summary

cd05503
Location:1780 → 1876

Bromo_BAZ2A_B_like; Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting ...

smart00571
Location:839 → 901

DDT; domain in different transcription and chromosome remodeling factors

PHA03307
Location:269 → 516

PHA03307; transcriptional regulator ICP4; Provisional

PRK07003
Location:407 → 533

PRK07003; DNA polymerase III subunit gamma/tau

cd01397
Location:541 → 613

HAT_MBD; Methyl-CpG binding domains (MBD) present in putative chromatin remodelling factor such as BAZ2A; BAZ2A contains a MBD, DDT, PHD-type zinc finger and Bromo domain suggesting that BAZ2A might be associated with histone acetyltransferase (HAT) activity. The ...

cd15629
Location:1662 → 1708

PHD_BAZ2A; PHD finger found in bromodomain adjacent to zinc finger domain protein 2A (BAZ2A)

pfam03154
Location:1150 → 1420

Atrophin-1; Atrophin-1 family

pfam15613
Location:1423 → 1457

WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
XM_011243284.4 → XP_011241586.1 bromodomain adjacent to zinc finger domain protein 2A isoform X1

See identical proteins and their annotated locations for XP_011241586.1

UniProtKB/TrEMBL

A0A1W2P6X9, E9Q374

Related

ENSMUSP00000151445.2, ENSMUST00000217851.2

Conserved Domains (8) summary

cd05503
Location:1781 → 1877

Bromo_BAZ2A_B_like; Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting ...

smart00571
Location:840 → 902

DDT; domain in different transcription and chromosome remodeling factors

PHA03307
Location:269 → 517

PHA03307; transcriptional regulator ICP4; Provisional

PRK07003
Location:408 → 534

PRK07003; DNA polymerase III subunit gamma/tau

cd01397
Location:542 → 614

HAT_MBD; Methyl-CpG binding domains (MBD) present in putative chromatin remodelling factor such as BAZ2A; BAZ2A contains a MBD, DDT, PHD-type zinc finger and Bromo domain suggesting that BAZ2A might be associated with histone acetyltransferase (HAT) activity. The ...

cd15629
Location:1663 → 1709

PHD_BAZ2A; PHD finger found in bromodomain adjacent to zinc finger domain protein 2A (BAZ2A)

pfam03154
Location:1151 → 1421

Atrophin-1; Atrophin-1 family

pfam15613
Location:1424 → 1458

WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
XM_011243286.4 → XP_011241588.1 bromodomain adjacent to zinc finger domain protein 2A isoform X2

See identical proteins and their annotated locations for XP_011241588.1

UniProtKB/TrEMBL

A0A5F8MPQ7, F8VPM0

Related

ENSMUSP00000151961.2, ENSMUST00000220049.2

Conserved Domains (8) summary

cd05503
Location:1780 → 1876

Bromo_BAZ2A_B_like; Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting ...

smart00571
Location:839 → 901

DDT; domain in different transcription and chromosome remodeling factors

PHA03307
Location:269 → 516

PHA03307; transcriptional regulator ICP4; Provisional

PRK07003
Location:407 → 533

PRK07003; DNA polymerase III subunit gamma/tau

cd01397
Location:541 → 613

HAT_MBD; Methyl-CpG binding domains (MBD) present in putative chromatin remodelling factor such as BAZ2A; BAZ2A contains a MBD, DDT, PHD-type zinc finger and Bromo domain suggesting that BAZ2A might be associated with histone acetyltransferase (HAT) activity. The ...

cd15629
Location:1662 → 1708

PHD_BAZ2A; PHD finger found in bromodomain adjacent to zinc finger domain protein 2A (BAZ2A)

pfam03154
Location:1150 → 1420

Atrophin-1; Atrophin-1 family

pfam15613
Location:1423 → 1457

WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
XM_030244835.2 → XP_030100695.1 bromodomain adjacent to zinc finger domain protein 2A isoform X2

UniProtKB/TrEMBL

A0A5F8MPQ7, F8VPM0

Conserved Domains (8) summary

cd05503
Location:1780 → 1876

Bromo_BAZ2A_B_like; Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting ...

smart00571
Location:839 → 901

DDT; domain in different transcription and chromosome remodeling factors

PHA03307
Location:269 → 516

PHA03307; transcriptional regulator ICP4; Provisional

PRK07003
Location:407 → 533

PRK07003; DNA polymerase III subunit gamma/tau

cd01397
Location:541 → 613

HAT_MBD; Methyl-CpG binding domains (MBD) present in putative chromatin remodelling factor such as BAZ2A; BAZ2A contains a MBD, DDT, PHD-type zinc finger and Bromo domain suggesting that BAZ2A might be associated with histone acetyltransferase (HAT) activity. The ...

cd15629
Location:1662 → 1708

PHD_BAZ2A; PHD finger found in bromodomain adjacent to zinc finger domain protein 2A (BAZ2A)

pfam03154
Location:1150 → 1420

Atrophin-1; Atrophin-1 family

pfam15613
Location:1423 → 1457

WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
XM_030244831.2 → XP_030100691.1 bromodomain adjacent to zinc finger domain protein 2A isoform X1

UniProtKB/TrEMBL

A0A1W2P6X9, E9Q374

Related

ENSMUSP00000129803.3, ENSMUST00000170054.9

Conserved Domains (8) summary

cd05503
Location:1781 → 1877

Bromo_BAZ2A_B_like; Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting ...

smart00571
Location:840 → 902

DDT; domain in different transcription and chromosome remodeling factors

PHA03307
Location:269 → 517

PHA03307; transcriptional regulator ICP4; Provisional

PRK07003
Location:408 → 534

PRK07003; DNA polymerase III subunit gamma/tau

cd01397
Location:542 → 614

HAT_MBD; Methyl-CpG binding domains (MBD) present in putative chromatin remodelling factor such as BAZ2A; BAZ2A contains a MBD, DDT, PHD-type zinc finger and Bromo domain suggesting that BAZ2A might be associated with histone acetyltransferase (HAT) activity. The ...

cd15629
Location:1663 → 1709

PHD_BAZ2A; PHD finger found in bromodomain adjacent to zinc finger domain protein 2A (BAZ2A)

pfam03154
Location:1151 → 1421

Atrophin-1; Atrophin-1 family

pfam15613
Location:1424 → 1458

WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
XM_030244834.2 → XP_030100694.1 bromodomain adjacent to zinc finger domain protein 2A isoform X2

UniProtKB/TrEMBL

A0A5F8MPQ7, F8VPM0

Conserved Domains (8) summary

cd05503
Location:1780 → 1876

Bromo_BAZ2A_B_like; Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting ...

smart00571
Location:839 → 901

DDT; domain in different transcription and chromosome remodeling factors

PHA03307
Location:269 → 516

PHA03307; transcriptional regulator ICP4; Provisional

PRK07003
Location:407 → 533

PRK07003; DNA polymerase III subunit gamma/tau

cd01397
Location:541 → 613

HAT_MBD; Methyl-CpG binding domains (MBD) present in putative chromatin remodelling factor such as BAZ2A; BAZ2A contains a MBD, DDT, PHD-type zinc finger and Bromo domain suggesting that BAZ2A might be associated with histone acetyltransferase (HAT) activity. The ...

cd15629
Location:1662 → 1708

PHD_BAZ2A; PHD finger found in bromodomain adjacent to zinc finger domain protein 2A (BAZ2A)

pfam03154
Location:1150 → 1420

Atrophin-1; Atrophin-1 family

pfam15613
Location:1423 → 1457

WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
XM_011243287.4 → XP_011241589.1 bromodomain adjacent to zinc finger domain protein 2A isoform X5

Conserved Domains (6) summary

cd05503
Location:1240 → 1336

Bromo_BAZ2A_B_like; Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting ...

smart00571
Location:299 → 361

DDT; domain in different transcription and chromosome remodeling factors

cd01397
Location:10 → 73

HAT_MBD; Methyl-CpG binding domains (MBD) present in putative chromatin remodelling factor such as BAZ2A; BAZ2A contains a MBD, DDT, PHD-type zinc finger and Bromo domain suggesting that BAZ2A might be associated with histone acetyltransferase (HAT) activity. The ...

cd15629
Location:1122 → 1168

PHD_BAZ2A; PHD finger found in bromodomain adjacent to zinc finger domain protein 2A (BAZ2A)

pfam03154
Location:610 → 880

Atrophin-1; Atrophin-1 family

pfam15613
Location:883 → 917

WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif