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    TXNRD1 thioredoxin reductase 1 [ Trachypithecus francoisi (Francois's langur) ]

    Gene ID: 117089505, updated on 11-Apr-2024

    Summary

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    Gene symbol
    TXNRD1
    Gene description
    thioredoxin reductase 1
    See related
    EnsemblRapid:ENSTFRG00000014257
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Trachypithecus francoisi
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Colobinae; Trachypithecus
    Orthologs
    human mouse all
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    Genomic context

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    See TXNRD1 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    100 current Tfra_2.0 (GCF_009764315.1) Unplaced Scaffold NW_022681456.1 (28949409..29086330, complement)

    NW_022681456.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC117089504 Neighboring gene carbohydrate sulfotransferase 11 Neighboring gene ATP synthase F(0) complex subunit C1, mitochondrial-like Neighboring gene 60S ribosomal protein L28-like Neighboring gene 60S ribosomal protein L9-like Neighboring gene EP300 interacting inhibitor of differentiation 3 Neighboring gene 60S ribosomal protein L28 Neighboring gene translation initiation factor IF-2-like Neighboring gene nuclear transcription factor Y subunit beta Neighboring gene host cell factor C2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_022681456 Unplaced Scaffold Reference Tfra_2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables flavin adenine dinucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables glutathione-disulfide reductase (NADPH) activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables thioredoxin-disulfide reductase (NADPH) activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell redox homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to oxidative stress IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in glutathione metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    thioredoxin reductase 1, cytoplasmic

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Trachypithecus francoisi Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Tfra_2.0 Primary Assembly

    Genomic

    1. NW_022681456.1 Reference Tfra_2.0 Primary Assembly

      Range
      28949409..29086330 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_033220823.1 → XP_033076714.1  thioredoxin reductase 1, cytoplasmic isoform X1

      Related
      ENSTFRP00000016935.1, ENSTFRT00000021185.1
      Conserved Domains (2) summary
      cd03419
      Location:68 → 148
      GRX_GRXh_1_2_like; Glutaredoxin (GRX) family, GRX human class 1 and 2 (h_1_2)-like subfamily; composed of proteins similar to human GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, ...
      TIGR01438
      Location:161 → 647
      TGR; thioredoxin and glutathione reductase selenoprotein

    2. XM_033220833.1 → XP_033076724.1  thioredoxin reductase 1, cytoplasmic isoform X4

      Conserved Domains (1) summary
      TIGR01438
      Location:11 → 497
      TGR; thioredoxin and glutathione reductase selenoprotein

    3. XM_033220826.1 → XP_033076717.1  thioredoxin reductase 1, cytoplasmic isoform X3

      Conserved Domains (1) summary
      TIGR01438
      Location:55 → 541
      TGR; thioredoxin and glutathione reductase selenoprotein

    4. XM_033220831.1 → XP_033076722.1  thioredoxin reductase 1, cytoplasmic isoform X4

      Conserved Domains (1) summary
      TIGR01438
      Location:11 → 497
      TGR; thioredoxin and glutathione reductase selenoprotein

    5. XM_033220824.1 → XP_033076715.1  thioredoxin reductase 1, cytoplasmic isoform X2

      Related
      ENSTFRP00000017088.1, ENSTFRT00000021392.1
      Conserved Domains (1) summary
      TIGR01438
      Location:145 → 631
      TGR; thioredoxin and glutathione reductase selenoprotein

    6. XM_033220829.1 → XP_033076720.1  thioredoxin reductase 1, cytoplasmic isoform X4

      Conserved Domains (1) summary
      TIGR01438
      Location:11 → 497
      TGR; thioredoxin and glutathione reductase selenoprotein

    7. XM_033220830.1 → XP_033076721.1  thioredoxin reductase 1, cytoplasmic isoform X4

      Conserved Domains (1) summary
      TIGR01438
      Location:11 → 497
      TGR; thioredoxin and glutathione reductase selenoprotein

    8. XM_033220827.1 → XP_033076718.1  thioredoxin reductase 1, cytoplasmic isoform X3

      Conserved Domains (1) summary
      TIGR01438
      Location:55 → 541
      TGR; thioredoxin and glutathione reductase selenoprotein

    9. XM_033220832.1 → XP_033076723.1  thioredoxin reductase 1, cytoplasmic isoform X4

      Conserved Domains (1) summary
      TIGR01438
      Location:11 → 497
      TGR; thioredoxin and glutathione reductase selenoprotein

    10. XM_033220828.1 → XP_033076719.1  thioredoxin reductase 1, cytoplasmic isoform X4

      Related
      ENSTFRP00000017013.1, ENSTFRT00000021291.1
      Conserved Domains (1) summary
      TIGR01438
      Location:11 → 497
      TGR; thioredoxin and glutathione reductase selenoprotein
    Nucleotide Protein
    Heading Accession and Version

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