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    SPIRE2 spire type actin nucleation factor 2 [ Trichosurus vulpecula (common brushtail) ]

    Gene ID: 118843256, updated on 20-Mar-2024

    Summary

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    Gene symbol
    SPIRE2
    Gene description
    spire type actin nucleation factor 2
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Trichosurus vulpecula
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Diprotodontia; Phalangeridae; Trichosurus
    Orthologs
    human mouse all
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    Genomic context

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    See SPIRE2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    100 current mTriVul1.pri (GCF_011100635.1) 3 NC_050575.1 (391659306..391715534)

    Chromosome 3 - NC_050575.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 276 Neighboring gene FA complementation group A Neighboring gene L-lactate dehydrogenase A chain-like Neighboring gene TCF25 ribosome quality control complex subunit Neighboring gene melanocortin 1 receptor

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_050575.1 Chromosome 3 Reference mTriVul1.pri Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Golgi vesicle transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in actin filament network formation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in actin filament polymerization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in actin nucleation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cleavage furrow formation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in establishment of meiotic spindle localization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in polar body extrusion after meiotic divisions IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell cortex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasmic vesicle membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein spire homolog 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Trichosurus vulpecula Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mTriVul1.pri Primary Assembly

    Genomic

    1. NC_050575.1 Reference mTriVul1.pri Primary Assembly

      Range
      391659306..391715534
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036750788.1 → XP_036606683.1  protein spire homolog 2

      Conserved Domains (6) summary
      cl28890
      Location:598 → 705
      FYVE_like_SF; FYVE domain like superfamily
      pfam16474
      Location:35 → 225
      KIND; Kinase non-catalytic C-lobe domain
      cd22065
      Location:250 → 281
      WH2_Spire_1-2_r1; first tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homologs 1 and 2
      cd22079
      Location:292 → 321
      WH2_Spire2_r2; second tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homolog 2
      cd22081
      Location:356 → 377
      WH2_Spire2_r4; fourth tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homolog 2
      cd22186
      Location:324 → 346
      WH2_Spire1-2_r3; third tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homologs 1 and 2
    Nucleotide Protein
    Heading Accession and Version

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