U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [ Talpa occidentalis (Iberian mole) ]

    Gene ID: 119245286, updated on 21-Mar-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    PIK3CG
    Gene description
    phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Talpa occidentalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Eulipotyphla; Talpidae; Talpa
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See PIK3CG in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2023_03 current MPIMG_talOcc4v2.1 (GCF_014898055.3) Unplaced Scaffold NW_026555331.1 (122825531..122856419)

    NW_026555331.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119245244 Neighboring gene nicotinamide phosphoribosyltransferase Neighboring gene coiled-coil domain containing 71 like Neighboring gene U6 spliceosomal RNA Neighboring gene protein kinase cAMP-dependent type II regulatory subunit beta Neighboring gene HMG-box transcription factor 1 Neighboring gene component of oligomeric golgi complex 5

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NW_026555331 Unplaced Scaffold Reference MPIMG_talOcc4v2.1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 1-phosphatidylinositol-3-kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables 1-phosphatidylinositol-4-phosphate 3-kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol-3-phosphate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol-mediated signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of phosphatidylinositol 3-kinase complex, class IA IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of phosphatidylinositol 3-kinase complex, class IB IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_014898055.3-RS_2023_03

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference MPIMG_talOcc4v2.1 Primary Assembly

    Genomic

    1. NW_026555331.1 Reference MPIMG_talOcc4v2.1 Primary Assembly

      Range
      122825531..122856419
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_037511504.2 → XP_037367401.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

      Conserved Domains (4) summary
      cd08399
      Location:350 → 527
      C2_PI3K_class_I_gamma; C2 domain present in class I gamma phosphatidylinositol 3-kinases (PI3Ks)
      smart00144
      Location:203 → 312
      PI3K_rbd; PI3-kinase family, Ras-binding domain
      cd00872
      Location:549 → 725
      PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
      cd00894
      Location:729 → 1095
      PI3Kc_IB_gamma; Catalytic domain of Class IB Phosphoinositide 3-kinase gamma

    2. XM_037511513.1 → XP_037367410.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

      Conserved Domains (4) summary
      cd08399
      Location:350 → 527
      C2_PI3K_class_I_gamma; C2 domain present in class I gamma phosphatidylinositol 3-kinases (PI3Ks)
      smart00144
      Location:203 → 312
      PI3K_rbd; PI3-kinase family, Ras-binding domain
      cd00872
      Location:549 → 725
      PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
      cd00894
      Location:729 → 1095
      PI3Kc_IB_gamma; Catalytic domain of Class IB Phosphoinositide 3-kinase gamma

    3. XM_037511528.1 → XP_037367425.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

      Conserved Domains (4) summary
      cd08399
      Location:350 → 527
      C2_PI3K_class_I_gamma; C2 domain present in class I gamma phosphatidylinositol 3-kinases (PI3Ks)
      smart00144
      Location:203 → 312
      PI3K_rbd; PI3-kinase family, Ras-binding domain
      cd00872
      Location:549 → 725
      PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
      cd00894
      Location:729 → 1095
      PI3Kc_IB_gamma; Catalytic domain of Class IB Phosphoinositide 3-kinase gamma
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.