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    LCP1 lymphocyte cytosolic protein 1 [ Talpa occidentalis (Iberian mole) ]

    Gene ID: 119258766, updated on 21-Mar-2024

    Summary

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    Gene symbol
    LCP1
    Gene description
    lymphocyte cytosolic protein 1
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Talpa occidentalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Eulipotyphla; Talpidae; Talpa
    Orthologs
    human mouse all
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    Genomic context

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    See LCP1 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    RS_2023_03 current MPIMG_talOcc4v2.1 (GCF_014898055.3) Unplaced Scaffold NW_023604861.1 (43159769..43316430, complement)

    NW_023604861.1Genomic Context describing neighboring genes Neighboring gene zinc finger CCCH-type containing 13 Neighboring gene carboxypeptidase B2 Neighboring gene leucine rich repeat containing 63 Neighboring gene sarcoglycan gamma Neighboring gene sacsin molecular chaperone Neighboring gene TNF receptor superfamily member 19

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_023604861 Unplaced Scaffold Reference MPIMG_talOcc4v2.1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin filament bundle assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in actin filament network formation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in actin filament IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in actin filament bundle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    plastin-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_014898055.3-RS_2023_03

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference MPIMG_talOcc4v2.1 Primary Assembly

    Genomic

    1. NW_023604861.1 Reference MPIMG_talOcc4v2.1 Primary Assembly

      Range
      43159769..43316430 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054687783.1 → XP_054543758.1  plastin-2

    2. XM_054687785.1 → XP_054543760.1  plastin-2

    3. XM_037527019.2 → XP_037382916.1  plastin-2

      Conserved Domains (5) summary
      cd00051
      Location:13 → 79
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:98 → 242
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21327
      Location:251 → 375
      CH_PLS2_rpt2; second calponin homology (CH) domain found in plastin-2
      cd21333
      Location:511 → 625
      CH_PLS2_rpt4; fourth calponin homology (CH) domain found in plastin-2
      cl00030
      Location:374 → 507
      CH_SF; calponin homology (CH) domain superfamily

    4. XM_054687782.1 → XP_054543757.1  plastin-2

    5. XM_054687787.1 → XP_054543762.1  plastin-2

    6. XM_054687784.1 → XP_054543759.1  plastin-2

    RNA

    1. XR_008549084.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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