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    OCRL OCRL inositol polyphosphate-5-phosphatase [ Motacilla alba alba ]

    Gene ID: 119695047, updated on 3-Aug-2024

    Summary

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    Gene symbol
    OCRL
    Gene description
    OCRL inositol polyphosphate-5-phosphatase
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Motacilla alba alba (sub-species: alba)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves; Passeriformes; Passeroidea; Motacillidae; Motacilla
    Orthologs
    human mouse all
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    Genomic context

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    See OCRL in Genome Data Viewer
    Location:
    chromosome: 4A
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    100 current Motacilla_alba_V1.0_pri (GCF_015832195.1) 4A NC_052045.1 (14436129..14458114)

    Chromosome 4A - NC_052045.1Genomic Context describing neighboring genes Neighboring gene peptidylprolyl cis/trans isomerase, NIMA-interacting 4 Neighboring gene ERCC excision repair 6 like, spindle assembly checkpoint helicase Neighboring gene apelin Neighboring gene X-prolyl aminopeptidase 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_052045.1 Chromosome 4A Reference Motacilla_alba_V1.0_pri Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables inositol phosphate phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in phosphatidylinositol dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    inositol polyphosphate 5-phosphatase OCRL

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Motacilla alba alba Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Motacilla_alba_V1.0_pri Primary Assembly

    Genomic

    1. NC_052045.1 Reference Motacilla_alba_V1.0_pri Primary Assembly

      Range
      14436129..14458114
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038122860.1 → XP_037978788.1  inositol polyphosphate 5-phosphatase OCRL isoform X3

      UniProtKB/TrEMBL
      A0A7K5CC07
      Conserved Domains (3) summary
      cd09093
      Location:236 → 530
      INPP5c_INPP5B; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins
      cd04380
      Location:665 → 888
      RhoGAP_OCRL1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in OCRL1-like proteins. OCRL1 (oculocerebrorenal syndrome of Lowe 1)-like proteins contain two conserved domains: a central inositol polyphosphate 5-phosphatase domain and ...
      pfam16726
      Location:17 → 116
      OCRL_clath_bd; Inositol polyphosphate 5-phosphatase clathrin binding domain

    2. XM_038122858.1 → XP_037978786.1  inositol polyphosphate 5-phosphatase OCRL isoform X1

      UniProtKB/TrEMBL
      A0A7K5CC07
      Conserved Domains (3) summary
      cd09093
      Location:236 → 530
      INPP5c_INPP5B; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins
      cd04380
      Location:665 → 896
      RhoGAP_OCRL1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in OCRL1-like proteins. OCRL1 (oculocerebrorenal syndrome of Lowe 1)-like proteins contain two conserved domains: a central inositol polyphosphate 5-phosphatase domain and ...
      pfam16726
      Location:17 → 116
      OCRL_clath_bd; Inositol polyphosphate 5-phosphatase clathrin binding domain

    3. XM_038122859.1 → XP_037978787.1  inositol polyphosphate 5-phosphatase OCRL isoform X2

      UniProtKB/TrEMBL
      A0A7K5CC07
      Conserved Domains (3) summary
      cd09093
      Location:235 → 529
      INPP5c_INPP5B; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins
      cd04380
      Location:664 → 895
      RhoGAP_OCRL1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in OCRL1-like proteins. OCRL1 (oculocerebrorenal syndrome of Lowe 1)-like proteins contain two conserved domains: a central inositol polyphosphate 5-phosphatase domain and ...
      pfam16726
      Location:17 → 115
      OCRL_clath_bd; Inositol polyphosphate 5-phosphatase clathrin binding domain

    4. XM_038122861.1 → XP_037978789.1  inositol polyphosphate 5-phosphatase OCRL isoform X4

      UniProtKB/TrEMBL
      A0A7K5CC07
      Conserved Domains (2) summary
      cd09093
      Location:75 → 369
      INPP5c_INPP5B; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins
      cd04380
      Location:504 → 735
      RhoGAP_OCRL1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in OCRL1-like proteins. OCRL1 (oculocerebrorenal syndrome of Lowe 1)-like proteins contain two conserved domains: a central inositol polyphosphate 5-phosphatase domain and ...
    Nucleotide Protein
    Heading Accession and Version

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