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    LOC121856923 digestive cysteine proteinase 3-like [ Homarus americanus (American lobster) ]

    Gene ID: 121856923, updated on 7-Dec-2023

    Summary

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    Gene symbol
    LOC121856923
    Gene description
    digestive cysteine proteinase 3-like
    Locus tag
    Hamer_G017694
    See related
    EnsemblRapid:LOC121856923
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Homarus americanus
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Multicrustacea; Malacostraca; Eumalacostraca; Eucarida; Decapoda; Pleocyemata; Astacidea; Nephropoidea; Nephropidae; Homarus
    Also known as
    LCP3; LCP3-L1
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    Genomic context

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    See LOC121856923 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    100 current GMGI_Hamer_2.0 (GCF_018991925.1) Unplaced Scaffold NW_024756871.1 (2662289..2664084)

    NW_024756871.1Genomic Context describing neighboring genes Neighboring gene peroxisome biogenesis factor 1-like Neighboring gene uncharacterized LOC121856925 Neighboring gene uncharacterized LOC121856961 Neighboring gene uncharacterized LOC121856924 Neighboring gene uncharacterized LOC121856962

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_024756871 Unplaced Scaffold Reference GMGI_Hamer_2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Purification and characterization of a digestive cysteine proteinase from the American lobster (Homarus americanus). Laycock MV, et al. Biochem J, 1989 Oct 15. PMID 2597115, Free PMC Article
    2. Molecular cloning of three cDNAs that encode cysteine proteinases in the digestive gland of the American lobster (Homarus americanus). Laycock MV, et al. FEBS Lett, 1991 Nov 4. PMID 1959590
    3. Molecular cloning of three cDNAs that encode cysteine proteinases in the digestive gland of the American lobster (Homarus americanus). Laycock MV, et al. FEBS Lett, 1992 Apr 13. PMID 1451782
    4. Neuropeptidergic Signaling in the American Lobster Homarus americanus: New Insights from High-Throughput Nucleotide Sequencing. Christie AE, et al. PLoS One, 2015. PMID 26716450, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cysteine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteolysis involved in protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in lysosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    LOW QUALITY PROTEIN: digestive cysteine proteinase 3-like
    Names
    Digestive cysteine proteinase 3
    Digestive cysteine proteinase 3-like 1
    cysteine proteinase preproenzyme

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Homarus americanus Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GMGI_Hamer_2.0 Primary Assembly

    Genomic

    1. NW_024756871.1 Reference GMGI_Hamer_2.0 Primary Assembly

      Range
      2662289..2664084
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_042352684.1 → XP_042208618.1  LOW QUALITY PROTEIN: digestive cysteine proteinase 3-like

      UniProtKB/Swiss-Prot
      P25784
      Related
      XP_042208618.1, XM_042352684.1
      Conserved Domains (2) summary
      smart00848
      Location:16 → 62
      Inhibitor_I29; Cathepsin propeptide inhibitor domain (I29)
      cd02248
      Location:93 → 302
      Peptidase_C1A; Peptidase C1A subfamily (MEROPS database nomenclature); composed of cysteine peptidases (CPs) similar to papain, including the mammalian CPs (cathepsins B, C, F, H, L, K, O, S, V, X and W). Papain is an endopeptidase with specific substrate preferences, ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P25784.1 GenPept UniProtKB/Swiss-Prot:P25784

    Gene LinkOut

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    Molecular Biology Databases