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    LARGE1 LARGE xylosyl- and glucuronyltransferase 1 [ Neogale vison (American mink) ]

    Gene ID: 122892160, updated on 22-Mar-2024

    Summary

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    Gene symbol
    LARGE1
    Gene description
    LARGE xylosyl- and glucuronyltransferase 1
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Neogale vison
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae; Mustelinae; Neogale
    Also known as
    LARGE
    Orthologs
    human mouse all
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    Genomic context

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    See LARGE1 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    100 current ASM_NN_V1 (GCF_020171115.1) 12 NC_058102.1 (13355307..13888747)

    Chromosome 12 - NC_058102.1Genomic Context describing neighboring genes Neighboring gene U4 spliceosomal RNA Neighboring gene intestine specific homeobox Neighboring gene small nucleolar RNA SNORA76 Neighboring gene sulfide:quinone oxidoreductase, mitochondrial Neighboring gene synapsin III Neighboring gene TIMP metallopeptidase inhibitor 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_058102.1 Chromosome 12 Reference ASM_NN_V1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables glucuronosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables xylosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein O-linked mannosylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    LARGE xylosyl- and glucuronyltransferase 1
    Names
    Glycosyltransferase-like protein LARGE1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Neovison vison Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM_NN_V1 Primary Assembly

    Genomic

    1. NC_058102.1 Reference ASM_NN_V1 Primary Assembly

      Range
      13355307..13888747
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_044228337.1 → XP_044084272.1  LARGE xylosyl- and glucuronyltransferase 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C7BZM6
      Conserved Domains (1) summary
      cd06431
      Location:175 → 454
      GT8_LARGE_C; LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis

    2. XM_044228338.1 → XP_044084273.1  LARGE xylosyl- and glucuronyltransferase 1 isoform X2

      UniProtKB/TrEMBL
      A0A8C7BZM6, A0A8C7C6B5
      Conserved Domains (2) summary
      cd06431
      Location:138 → 417
      GT8_LARGE_C; LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis
      pfam13896
      Location:473 → 742
      Glyco_transf_49; Glycosyl-transferase for dystroglycan
    Nucleotide Protein
    Heading Accession and Version

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