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    SMO smoothened, frizzled class receptor [ Mauremys mutica (yellowpond turtle) ]

    Gene ID: 123376239, updated on 22-Mar-2024

    Summary

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    Gene symbol
    SMO
    Gene description
    smoothened, frizzled class receptor
    Locus tag
    KIL84_018460
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Mauremys mutica
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira; Testudinoidea; Geoemydidae; Geoemydinae; Mauremys
    Orthologs
    human mouse all
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    Genomic context

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    See SMO in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    100 current ASM2049712v1 (GCF_020497125.1) 1 NC_059072.1 (5955433..5990490)

    Chromosome 1 - NC_059072.1Genomic Context describing neighboring genes Neighboring gene immunoglobulin lambda-1 light chain-like Neighboring gene tetraspanin 33 Neighboring gene uncharacterized LOC123376347 Neighboring gene adenosylhomocysteinase like 2 Neighboring gene striatin interacting protein 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_059072.1 Chromosome 1 Reference ASM2049712v1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables patched binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transmembrane signaling receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in central nervous system development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in commissural neuron axon guidance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of smoothened signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in smoothened signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cilium IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in dendrite IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    smoothened homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Mauremys mutica Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM2049712v1 Primary Assembly

    Genomic

    1. NC_059072.1 Reference ASM2049712v1 Primary Assembly

      Range
      5955433..5990490
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_045028123.1 → XP_044884058.1  smoothened homolog

      UniProtKB/TrEMBL
      A0A9D3XT61, A0A9D4BAT5
      Conserved Domains (2) summary
      cd07451
      Location:67 → 197
      CRD_SMO; Cysteine-rich domain of the smoothened receptor (Smo) integral membrane protein
      cd15030
      Location:221 → 551
      7tmF_SMO_homolog; class F smoothened family membrane region, a homolog of frizzled receptors
    Nucleotide Protein
    Heading Accession and Version

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