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    Y53C12A.10 tRNA-uridine aminocarboxypropyltransferase 1 [ Caenorhabditis elegans ]

    Gene ID: 13186571, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y53C12A.10
    Official Full Name
    tRNA-uridine aminocarboxypropyltransferase 1
    Primary source
    WormBase:WBGene00175030
    Locus tag
    CELE_Y53C12A.10
    See related
    AllianceGenome:WB:WBGene00175030
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable tRNA-uridine aminocarboxypropyltransferase activity. Predicted to be involved in tRNA modification. Predicted to be active in nucleus. Orthologous to human DTWD1 (DTW domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y53C12A.10 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_003280.10 (9703812..9704846, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Expressed conserved protein Neighboring gene HEAT repeat-containing protein Neighboring gene MO25-like protein 2 Neighboring gene Protein YIPF Neighboring gene Amino acid transporter

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    2. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables tRNA-uridine aminocarboxypropyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables tRNA-uridine aminocarboxypropyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in tRNA modification IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in tRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    tRNA-uridine aminocarboxypropyltransferase 1
    NP_001254222.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      9703812..9704846 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001267293.3 → NP_001254222.1  tRNA-uridine aminocarboxypropyltransferase 1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001254222.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7WNB4
      Conserved Domains (1) summary
      pfam03942
      Location:33 → 209
      DTW; DTW domain
    Nucleotide Protein
    Heading Accession and Version

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