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    cdk-14 Protein kinase domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 171672, updated on 9-Dec-2024

    Summary

    Official Symbol
    cdk-14
    Official Full Name
    Protein kinase domain-containing protein
    Primary source
    WormBase:WBGene00022519
    Locus tag
    CELE_ZC123.4
    See related
    AllianceGenome:WB:WBGene00022519
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable cyclin binding activity and cyclin-dependent protein serine/threonine kinase activity. Predicted to be involved in regulation of cell cycle phase transition. Predicted to be active in cytosol and nucleus. Orthologous to human CDK14 (cyclin dependent kinase 14) and CDK15 (cyclin dependent kinase 15). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See cdk-14 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    10
    Sequence:
    Chromosome: I; NC_003279.8 (841742..846763, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Zinc Finger and Homeobox;Zinc finger homeobox protein 4;Zinc finger protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Sperm mitochondrial-associated cysteine-rich protein-like Neighboring gene ncRNA Neighboring gene DZF domain-containing protein Neighboring gene Phosphodiesterase;putative 3',5'-cyclic phosphodiesterase pde-6 Neighboring gene Bursicon;Bursicon subunit alpha;Secreted protein Neighboring gene FBD domain-containing protein

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables cyclin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables cyclin-dependent protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of cell cycle phase transition IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    Protein kinase domain-containing protein
    NP_001382289.1
    • Confirmed by transcript evidence
    NP_001382290.1
    • Confirmed by transcript evidence
    NP_490783.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      841742..846763 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058382.5NP_490783.3  Protein kinase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_490783.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2L0S6
      Conserved Domains (1) summary
      cl21453
      Location:216506
      PKc_like; Protein Kinases, catalytic domain
    2. NM_001395341.1NP_001382289.1  Protein kinase domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2L0S7
      Conserved Domains (1) summary
      cl21453
      Location:132422
      PKc_like; Protein Kinases, catalytic domain
    3. NM_001395342.1NP_001382290.1  Protein kinase domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q65CM2
      Conserved Domains (1) summary
      cl21453
      Location:60350
      PKc_like; Protein Kinases, catalytic domain