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    cut-3 Cuticlin-3 [ Caenorhabditis elegans ]

    Gene ID: 174347, updated on 9-Dec-2024

    Summary

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    Official Symbol
    cut-3
    Official Full Name
    Cuticlin-3
    Primary source
    WormBase:WBGene00009041
    Locus tag
    CELE_F22B5.3
    See related
    AllianceGenome:WB:WBGene00009041
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be a structural constituent of cuticle. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See cut-3 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    4
    Sequence:
    Chromosome: II; NC_003280.10 (8445169..8446831, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene LIPaSe related Neighboring gene Eukaryotic translation initiation factor 3 subunit G Neighboring gene ADP-ribosylation factor-like protein 2 Neighboring gene Mitochondrial cytochrome c oxidase subunit VIa Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene DUF1248 domain-containing protein Neighboring gene Serpentine Receptor, class J

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Zona Pellucida domain containing proteins, CUT-1, CUT-3 and CUT-5, play essential roles in the development of the larval alae in Caenorhabditis elegans. Sapio MR, et al. Dev Biol, 2005 Jun 1. PMID 15936343
    2. Toxic Effects of Size-tunable Gold Nanoparticles on Caenorhabditis elegans Development and Gene Regulation. Hu CC, et al. Sci Rep, 2018 Oct 15. PMID 30323250, Free PMC Article
    3. Identification and characterization of epicuticular proteins of nematodes sharing motifs with cuticular proteins of arthropods. Betschart B, et al. PLoS One, 2022. PMID 36301857, Free PMC Article
    4. The effect of high strength static magnetic fields and ionizing radiation on gene expression and DNA damage in Caenorhabditis elegans. Kimura T, et al. Bioelectromagnetics, 2008 Dec. PMID 18512716
    5. Screening for cold tolerance genes in C. elegans, whose expressions are affected by anticancer drugs camptothecin and leptomycin B. Okahata M, et al. Sci Rep, 2024 Mar 5. PMID 38443452, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables structural constituent of cuticle IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Cuticlin-3
    NP_495780.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      8445169..8446831 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063379.8 → NP_495780.1  Cuticlin-3 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495780.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q19707
      Conserved Domains (1) summary
      smart00241
      Location:33 → 272
      ZP; Zona pellucida (ZP) domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q19707.1

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