npp-16 Nuclear pore complex protein npp-16 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: npp-16
Official Full Name: Nuclear pore complex protein npp-16
Primary source: WormBase:WBGene00003802
Locus tag: CELE_Y56A3A.17
See related: AllianceGenome:WB:WBGene00003802
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to be involved in protein import into nucleus. Predicted to be located in nuclear membrane. Predicted to be part of nuclear pore. Orthologous to human NUP50 (nucleoporin 50). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See npp-16 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 4

Sequence:: Chromosome: III; NC_003281.10 (11915928..11917873)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

NPP-16 and CDK-1 function to arrest prophase blastomeres in C. elegans embryos
Title: NPP-16/Nup50 function and CDK-1 inactivation are associated with anoxia-induced prophase arrest in Caenorhabditis elegans.

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

Y56A3A.19 (e-PCR)
- UniSTS:321874

Y56A3A.17A (e-PCR)
- UniSTS:321765

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Process	Evidence Code	Pubs
involved_in mRNA transport	IEA Inferred from Electronic Annotation more info
involved_in protein import into nucleus	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in nuclear membrane	IEA Inferred from Electronic Annotation more info
part_of nuclear pore	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Nuclear pore complex protein npp-16

NP_499551.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

11915928..11917873

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_067150.3 → NP_499551.1 Nuclear pore complex protein npp-16 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_499551.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q7K6X4

Conserved Domains (1) summary

cd13170
Location:387 → 496

RanBD_NUP50; Nucleoporin 50 Ran-binding domain