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    C18H7.1 VWFA domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 176888, updated on 9-Dec-2024

    Summary

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    Official Symbol
    C18H7.1
    Official Full Name
    VWFA domain-containing protein
    Primary source
    WormBase:WBGene00015993
    Locus tag
    CELE_C18H7.1
    See related
    AllianceGenome:WB:WBGene00015993
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be an extracellular matrix structural constituent. Predicted to be involved in extracellular matrix organization. Predicted to be located in collagen-containing extracellular matrix. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See C18H7.1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    9
    Sequence:
    Chromosome: IV; NC_003282.8 (615544..620936)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Nematode cuticle collagen N-terminal domain-containing protein Neighboring gene ncRNA Neighboring gene Innexin Neighboring gene tRNA-Val Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Nuclear hormone receptor family member nhr-76

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The in-silico characterization of the Caenorhabditis elegans matrisome and proposal of a novel collagen classification. Teuscher AC, et al. Matrix Biol Plus, 2019 Feb. PMID 33543001, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables extracellular matrix structural constituent RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in extracellular matrix organization RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in collagen-containing extracellular matrix RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    VWFA domain-containing protein
    NP_001294297.1
    • Confirmed by transcript evidence
    NP_001368221.1
    • Confirmed by transcript evidence
    NP_499959.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      615544..620936
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_067558.6 → NP_499959.1  VWFA domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_499959.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9GZF5
      Conserved Domains (1) summary
      cd01476
      Location:34 → 193
      VWA_integrin_invertebrates; VWA_integrin (invertebrates): Integrins are a family of cell surface receptors that have diverse functions in cell-cell and cell-extracellular matrix interactions. Because of their involvement in many biologically important adhesion processes, integrins ...

    2. NM_001307368.3 → NP_001294297.1  VWFA domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294297.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PB74
      Conserved Domains (1) summary
      cd01476
      Location:30 → 189
      VWA_integrin_invertebrates; VWA_integrin (invertebrates): Integrins are a family of cell surface receptors that have diverse functions in cell-cell and cell-extracellular matrix interactions. Because of their involvement in many biologically important adhesion processes, integrins ...

    3. NM_001380013.1 → NP_001368221.1  VWFA domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PQZ9
      Conserved Domains (2) summary
      cd01476
      Location:113 → 281
      VWA_integrin_invertebrates; VWA_integrin (invertebrates): Integrins are a family of cell surface receptors that have diverse functions in cell-cell and cell-extracellular matrix interactions. Because of their involvement in many biologically important adhesion processes, integrins ...
      cl00057
      Location:2 → 68
      vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    Nucleotide Protein
    Heading Accession and Version

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