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    mob-3 MOB kinase activator-like 3 [ Caenorhabditis elegans ]

    Gene ID: 177511, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mob-3
    Official Full Name
    MOB kinase activator-like 3
    Primary source
    WormBase:WBGene00020447
    Locus tag
    CELE_T12B3.4
    See related
    AllianceGenome:WB:WBGene00020447
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein kinase activator activity. Predicted to be involved in signal transduction. Predicted to be active in cytoplasm and nucleus. Orthologous to several human genes including MOB3A (MOB kinase activator 3A) and MOB3B (MOB kinase activator 3B). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See mob-3 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    8
    Sequence:
    Chromosome: IV; NC_003282.8 (7384756..7388943, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Major facilitator superfamily (MFS) profile domain-containing protein Neighboring gene TYR_PHOSPHATASE_2 domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The CeCDC-14 phosphatase is required for cytokinesis in the Caenorhabditis elegans embryo. Gruneberg U, et al. J Cell Biol, 2002 Sep 2. PMID 12213836, Free PMC Article
    2. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    3. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    MOB kinase activator-like 3
    NP_001294204.1
    • Confirmed by transcript evidence
    NP_501179.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      7384756..7388943 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_068778.4 → NP_501179.1  MOB kinase activator-like 3 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501179.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9UAX1
      Conserved Domains (1) summary
      pfam03637
      Location:95 → 267
      Mob1_phocein; Mob1/phocein family

    2. NM_001307275.5 → NP_001294204.1  MOB kinase activator-like 3 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294204.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      W6RY92
      Conserved Domains (1) summary
      pfam03637
      Location:36 → 208
      Mob1_phocein; Mob1/phocein family
    Nucleotide Protein
    Heading Accession and Version

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