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    C06A6.2 MADF domain-containing protein;WH2 domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 177573, updated on 9-Dec-2024

    Summary

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    Official Symbol
    C06A6.2
    Official Full Name
    MADF domain-containing protein;WH2 domain-containing protein
    Primary source
    WormBase:WBGene00015507
    Locus tag
    CELE_C06A6.2
    See related
    AllianceGenome:WB:WBGene00015507
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See C06A6.2 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    11
    Sequence:
    Chromosome: IV; NC_003282.8 (7846622..7854409)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene FMRF-Like Peptide

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Protein interaction mapping in C. elegans using proteins involved in vulval development. Walhout AJ, et al. Science, 2000 Jan 7. PMID 10615043
    2. SH3 interactome conserves general function over specific form. Xin X, et al. Mol Syst Biol, 2013. PMID 23549480, Free PMC Article
    3. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    4. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of transcription regulator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    MADF domain-containing protein;WH2 domain-containing protein
    NP_001294141.1
    • Confirmed by transcript evidence
    NP_001294197.1
    • Confirmed by transcript evidence
    NP_001368435.1
    • Confirmed by transcript evidence
    NP_001368436.1
    • Confirmed by transcript evidence
    NP_741449.2
    • Confirmed by transcript evidence
    NP_741450.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      7846622..7854409
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_171386.7 → NP_741449.2  MADF domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_741449.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2KYH8
      Conserved Domains (1) summary
      cl23759
      Location:250 → 338
      GT1; GT1, myb-like, SANT family

    2. NM_171911.7 → NP_741450.2  MADF domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_741450.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MQE8
      Conserved Domains (1) summary
      cl23759
      Location:250 → 338
      GT1; GT1, myb-like, SANT family

    3. NM_001380343.1 → NP_001368435.1  MADF domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      W6RQS3

    4. NM_001307212.3 → NP_001294141.1  WH2 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294141.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      W6RXT0

    5. NM_001307268.3 → NP_001294197.1  MADF domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294197.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      W6RTM8

    6. NM_001380344.1 → NP_001368436.1  WH2 domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      W6RRQ8
    Nucleotide Protein
    Heading Accession and Version

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