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    ins-1 Insulin-like domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 177936, updated on 9-Dec-2024

    Summary

    Official Symbol
    ins-1
    Official Full Name
    Insulin-like domain-containing protein
    Primary source
    WormBase:WBGene00002084
    Locus tag
    CELE_F13B12.5
    See related
    AllianceGenome:WB:WBGene00002084
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable hormone activity. Involved in several processes, including learning or memory; negative regulation of insulin receptor signaling pathway; and regulation of dauer entry. Located in several cellular components, including cytoplasmic vesicle; neuron projection; and neuronal cell body. Is expressed in several structures, including distal tip cell; egg-laying apparatus; head muscle; neurons; and somatic nervous system. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See ins-1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    3
    Sequence:
    Chromosome: IV; NC_003282.8 (10436701..10438412)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Major facilitator superfamily (MFS) profile domain-containing protein Neighboring gene ncRNA Neighboring gene Ion transport domain-containing protein Neighboring gene ncRNA Neighboring gene Neprosin domain-containing protein Neighboring gene Putative pyridoxal-phosphate dependent protein F13B12.4

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    General gene information

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables hormone activity  
    Component Evidence Code Pubs
    located_in cytoplasmic vesicle PubMed 
    located_in extracellular region  
    located_in neuron projection PubMed 
    located_in neuronal cell body PubMed 
    located_in synapse PubMed 

    General protein information

    Preferred Names
    Insulin-like domain-containing protein
    NP_501926.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      10436701..10438412
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_069525.6NP_501926.1  Insulin-like domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501926.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EFY8
      Conserved Domains (1) summary
      cd04366
      Location:34103
      IlGF_insulin_bombyxin_like; IlGF_like family, insulin_bombyxin_like subgroup. Members include a number of peptides including insulin, insulin-like growth factors I and II, insect prothoracicotropic hormone (bombyxin), locust insulin-related peptide (LIRP), molluscan insulin-related ...
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