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    lbp-9 Cytosolic fatty-acid binding proteins domain-containing protein;Fatty acid-binding protein homolog 9 [ Caenorhabditis elegans ]

    Gene ID: 178686, updated on 9-Dec-2024

    Summary

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    Official Symbol
    lbp-9
    Official Full Name
    Cytosolic fatty-acid binding proteins domain-containing protein;Fatty acid-binding protein homolog 9
    Primary source
    WormBase:WBGene00021486
    Locus tag
    CELE_Y40B10A.1
    See related
    AllianceGenome:WB:WBGene00021486
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable fatty acid binding activity. Predicted to be involved in fatty acid transport. Predicted to be active in cytosol and nucleus. Orthologous to human FABP4 (fatty acid binding protein 4). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See lbp-9 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    3
    Sequence:
    Chromosome: V; NC_003283.11 (2068449..2069142)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene O-methyltransferase Neighboring gene Catechol O-methyltransferase domain-containing protein 1 Neighboring gene Nuclear hormone receptor family member nhr-86 Neighboring gene Lipase_GDSL domain-containing protein;Phospholipase B1, membrane-associated Neighboring gene Glycosyltransferase family 92 protein Neighboring gene Glycosyltransferase family 92 protein Neighboring gene C2H2-type domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Caenorhabditis elegans as a screening tool for the endothelial cell-derived putative aging-related proteins detected by proteomic analysis. Ha MK, et al. Proteomics, 2006 Jun. PMID 16673436
    2. ω-6 Polyunsaturated fatty acids extend life span through the activation of autophagy. O'Rourke EJ, et al. Genes Dev, 2013 Feb 15. PMID 23392608, Free PMC Article
    3. Analysis of acidic peptides with a matrix-assisted laser desorption/ionization mass spectrometry using positive and negative ion modes with additive monoammonium phosphate. Nabetani T, et al. Proteomics, 2006 Aug. PMID 16897684
    4. A Caenorhabditis elegans nutrient response system partially dependent on nuclear receptor NHR-49. Van Gilst MR, et al. Proc Natl Acad Sci U S A, 2005 Sep 20. PMID 16157872, Free PMC Article
    5. Adult-restricted gene knock-down reveals candidates that affect locomotive healthspan in C. elegans. Jushaj A, et al. Biogerontology, 2023 Apr. PMID 36662373

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables fatty acid binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in fatty acid transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Cytosolic fatty-acid binding proteins domain-containing protein;Fatty acid-binding protein homolog 9
    NP_001033511.1
    • Confirmed by transcript evidence
    NP_001033512.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      2068449..2069142
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001038422.7 → NP_001033511.1  Fatty acid-binding protein homolog 9 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001033511.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q965W1
      Conserved Domains (1) summary
      pfam00061
      Location:23 → 151
      Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family

    2. NM_001038423.6 → NP_001033512.1  Cytosolic fatty-acid binding proteins domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001033512.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q3LFN1
      Conserved Domains (1) summary
      cd00742
      Location:6 → 135
      FABP; intracellular fatty acid-binding protein family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q965W1.1

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