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    vap-2 SCP domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 181273, updated on 2-Nov-2024

    Summary

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    Official Symbol
    vap-2
    Official Full Name
    SCP domain-containing protein
    Primary source
    WormBase:WBGene00011462
    Locus tag
    CELE_T05A10.5
    See related
    AllianceGenome:WB:WBGene00011462
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in extracellular region and membrane. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See vap-2 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    12
    Sequence:
    Chromosome: X; NC_003284.9 (10789611..10792535, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Transcription factor sma-9 Neighboring gene CLaudin-like in Caenorhabditis Neighboring gene Transthyretin-like family protein Neighboring gene DUF19 domain-containing protein Neighboring gene ncRNA Neighboring gene 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1;Phosphoinositide phospholipase C

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The barber's pole worm CAP protein superfamily--A basis for fundamental discovery and biotechnology advances. Mohandas N, et al. Biotechnol Adv, 2015 Dec. PMID 26239368
    2. CAP protein superfamily members in Toxocara canis. Stroehlein AJ, et al. Parasit Vectors, 2016 Jun 24. PMID 27342979, Free PMC Article
    3. Distinct patterns of gene and protein expression elicited by organophosphorus pesticides in Caenorhabditis elegans. Lewis JA, et al. BMC Genomics, 2009 Apr 29. PMID 19402892, Free PMC Article
    4. Transcriptomics of ivermectin response in Caenorhabditis elegans: Integrating abamectin quantitative trait loci and comparison to the Ivermectin-exposed DA1316 strain. Dube F, et al. PLoS One, 2023. PMID 37141255, Free PMC Article
    5. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    SCP domain-containing protein
    NP_001300377.1
    • Partially confirmed by transcript evidence
    NP_001300378.1
    • Confirmed by transcript evidence
    NP_509802.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      10789611..10792535 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_077401.7 → NP_509802.2  SCP domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_509802.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7VCA9, P90958
      Conserved Domains (1) summary
      smart00198
      Location:281 → 434
      SCP; SCP / Tpx-1 / Ag5 / PR-1 / Sc7 family of extracellular domains

    2. NM_001313448.4 → NP_001300377.1  SCP domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0K3AST9, B7VCA9
      Conserved Domains (1) summary
      smart00198
      Location:315 → 468
      SCP; SCP / Tpx-1 / Ag5 / PR-1 / Sc7 family of extracellular domains

    3. NM_001313449.4 → NP_001300378.1  SCP domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0K3AWG2
      Conserved Domains (2) summary
      smart00198
      Location:185 → 338
      SCP; SCP / Tpx-1 / Ag5 / PR-1 / Sc7 family of extracellular domains
      cl00133
      Location:2 → 123
      SCP; SCP: SCP-like extracellular protein domain, found in eukaryotes and prokaryotes. This family includes plant pathogenesis-related protein 1 (PR-1), which accumulates after infections with pathogens, and may act as an anti-fungal agent or be involved in ...
    Nucleotide Protein
    Heading Accession and Version

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