vwa-8 ATPase dynein-related AAA domain-containing protein;VWFA domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: vwa-8
Official Full Name: ATPase dynein-related AAA domain-containing protein;VWFA domain-containing protein
Primary source: WormBase:WBGene00008694
Locus tag: CELE_F11C1.5
See related: AllianceGenome:WB:WBGene00008694
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable ATP binding activity and ATP hydrolysis activity. Predicted to be active in cytoplasm. Is expressed in hypodermal cell; intestine; muscle cell; and pharynx. Orthologous to human VWA8 (von Willebrand factor A domain containing 8). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See vwa-8 in Genome Data Viewer

Location:: chromosome: X

Exon count:: 28

Sequence:: Chromosome: X; NC_003284.9 (12991470..12999632)

Chromosome X - NC_003284.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F11C1.5 (e-PCR)
- UniSTS:307465

STS6-192 (e-PCR)
- UniSTS:242576

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables ATP hydrolysis activity	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: ATPase dynein-related AAA domain-containing protein;VWFA domain-containing protein

NP_001368181.1

Confirmed by transcript evidence

NP_510160.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003284.9 Reference assembly

Range

12991470..12999632

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001381128.1 → NP_001368181.1 ATPase dynein-related AAA domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

S6EZK7

Conserved Domains (1) summary

pfam07728
Location:78 → 234

AAA_5; AAA domain (dynein-related subfamily)
NM_077759.8 → NP_510160.2 VWFA domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_510160.2

Status: REVIEWED

UniProtKB/TrEMBL

Q19346

Conserved Domains (2) summary

pfam07728
Location:78 → 234

AAA_5; AAA domain (dynein-related subfamily)

cl00057
Location:1612 → 1803

vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...