snrpc small nuclear ribonucleoprotein polypeptide C [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: snrpcprovided by ZNC
Official Full Name: small nuclear ribonucleoprotein polypeptide Cprovided by ZNC
Primary source: ZFIN:ZDB-GENE-020419-26
See related: Ensembl:ENSDARG00000009871 AllianceGenome:ZFIN:ZDB-GENE-020419-26
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: U1C; U1-C; chunp6909; zgc:109792
Summary: Predicted to enable pre-mRNA 5'-splice site binding activity. Acts upstream of or within regulation of alternative mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of U1 snRNP. Human ortholog(s) of this gene implicated in connective tissue disease; mixed connective tissue disease; and systemic lupus erythematosus. Orthologous to human SNRPC (small nuclear ribonucleoprotein polypeptide C). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 6

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	6	NC_007117.7 (54430413..54433968, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	6	NC_007117.6 (54422305..54425860, complement)

Chromosome 6 - NC_007117.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables U1 snRNA binding	IEA Inferred from Electronic Annotation more info
enables mRNA binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info
enables pre-mRNA 5'-splice site binding	IBA Inferred from Biological aspect of Ancestor more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in mRNA 5'-splice site recognition	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within mRNA splicing, via spliceosome	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of alternative mRNA splicing, via spliceosome	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within spliceosomal snRNP assembly	IEA Inferred from Electronic Annotation more info
involved_in spliceosomal snRNP assembly	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of U1 snRNP	IBA Inferred from Biological aspect of Ancestor more info
part_of U1 snRNP	IEA Inferred from Electronic Annotation more info
part_of U1 snRNP	ISS Inferred from Sequence or Structural Similarity more info
part_of U2-type prespliceosome	IEA Inferred from Electronic Annotation more info
part_of commitment complex	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: U1 small nuclear ribonucleoprotein C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.