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    Tceal1 transcription elongation factor A (SII)-like 1 [ Mus musculus (house mouse) ]

    Gene ID: 237052, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Tceal1provided by MGI
    Official Full Name
    transcription elongation factor A (SII)-like 1provided by MGI
    Primary source
    MGI:MGI:2385317
    See related
    Ensembl:ENSMUSG00000049536 AllianceGenome:MGI:2385317
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    P21; SIIR; pp21; 0610011M09Rik
    Summary
    Predicted to be located in nucleoplasm. Is expressed in several structures, including foregut; ganglia; lung; remnant of Rathke's pouch; and sensory organ. Orthologous to human TCEAL1 (transcription elongation factor A like 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in CNS E18 (RPKM 10.2), frontal lobe adult (RPKM 9.5) and 19 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Tceal1 in Genome Data Viewer
    Location:
    X F1; X 59.1 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (135608731..135610622)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (136707982..136709873)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene transcription elongation factor A (SII)-like 3 Neighboring gene acyl-protein thioesterase 1 pseudogene Neighboring gene predicted gene, 39536 Neighboring gene STARR-seq mESC enhancer starr_47978 Neighboring gene STARR-positive B cell enhancer ABC_E3262 Neighboring gene STARR-positive B cell enhancer ABC_E11056 Neighboring gene mortality factor 4 like 2 Neighboring gene cDNA sequence BC065397 Neighboring gene glycine receptor, alpha 4 subunit Neighboring gene predicted gene, 54085

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Characterization of an eutherian gene cluster generated after transposon domestication identifies Bex3 as relevant for advanced neurological functions. Navas-Pérez E, et al. Genome Biol, 2020 Oct 26. PMID 33100228, Free PMC Article
    2. The human (PEDB) and mouse (mPEDB) Prostate Expression Databases. Nelson PS, et al. Nucleic Acids Res, 2002 Jan 1. PMID 11752298, Free PMC Article
    3. Protein-protein interaction panel using mouse full-length cDNAs. Suzuki H, et al. Genome Res, 2001 Oct. PMID 11591653, Free PMC Article
    4. USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities. Liu C, et al. Sci Adv, 2023 May 19. PMID 37196079, Free PMC Article
    5. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Clone Names

    • MGC18752, MGC102312

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    transcription elongation factor A protein-like 1
    Names
    TCEA-like protein 1
    transcription elongation factor S-II protein-like 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001356367.1 → NP_001343296.1  transcription elongation factor A protein-like 1

      Status: VALIDATED

      Source sequence(s)
      AL671887, CK618090, DV057188
      Consensus CDS
      CCDS30421.1
      UniProtKB/Swiss-Prot
      Q921P9
      Conserved Domains (1) summary
      pfam04538
      Location:93 → 165
      BEX; Brain expressed X-linked like family

    2. NM_146236.2 → NP_666348.1  transcription elongation factor A protein-like 1

      See identical proteins and their annotated locations for NP_666348.1

      Status: VALIDATED

      Source sequence(s)
      AL671887, CK618090, DV051075
      Consensus CDS
      CCDS30421.1
      UniProtKB/Swiss-Prot
      Q921P9
      Related
      ENSMUSP00000061875.6, ENSMUST00000055104.6
      Conserved Domains (1) summary
      pfam04538
      Location:93 → 165
      BEX; Brain expressed X-linked like family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      135608731..135610622
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030251327.1 → XP_030107187.1  transcription elongation factor A protein-like 1 isoform X1

      UniProtKB/Swiss-Prot
      Q921P9
      Conserved Domains (1) summary
      pfam04538
      Location:93 → 165
      BEX; Brain expressed X-linked like family

    2. XM_006528517.4 → XP_006528580.1  transcription elongation factor A protein-like 1 isoform X1

      See identical proteins and their annotated locations for XP_006528580.1

      UniProtKB/Swiss-Prot
      Q921P9
      Conserved Domains (1) summary
      pfam04538
      Location:93 → 165
      BEX; Brain expressed X-linked like family
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q921P9.1 GenPept UniProtKB/Swiss-Prot:Q921P9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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