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    Plcxd3 phosphatidylinositol-specific phospholipase C, X domain containing 3 [ Mus musculus (house mouse) ]

    Gene ID: 239318, updated on 27-Nov-2024

    Summary

    Official Symbol
    Plcxd3provided by MGI
    Official Full Name
    phosphatidylinositol-specific phospholipase C, X domain containing 3provided by MGI
    Primary source
    MGI:MGI:2442605
    See related
    Ensembl:ENSMUSG00000049148 AllianceGenome:MGI:2442605
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    B130016O10Rik
    Summary
    Predicted to enable phosphoric diester hydrolase activity. Predicted to be involved in lipid catabolic process and signal transduction. Is active in glutamatergic synapse. Is expressed in telencephalon. Orthologous to human PLCXD3 (phosphatidylinositol specific phospholipase C X domain containing 3). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in cerebellum adult (RPKM 3.6), CNS E18 (RPKM 2.2) and 8 other tissues See more
    Orthologs
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    Genomic context

    See Plcxd3 in Genome Data Viewer
    Location:
    15 A1; 15 1.96 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (4404973..4605067)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (4375491..4575585)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_37819 Neighboring gene predicted gene 2093 Neighboring gene 3-oxoacid CoA transferase 1 antisense RNA Neighboring gene 3-oxoacid CoA transferase 1 Neighboring gene STARR-seq mESC enhancer starr_37822 Neighboring gene STARR-seq mESC enhancer starr_37823 Neighboring gene STARR-seq mESC enhancer starr_37824 Neighboring gene STARR-seq mESC enhancer starr_37825 Neighboring gene STARR-seq mESC enhancer starr_37827 Neighboring gene STARR-seq mESC enhancer starr_37828 Neighboring gene STARR-seq mESC enhancer starr_37829 Neighboring gene STARR-seq mESC enhancer starr_37830 Neighboring gene STARR-seq mESC enhancer starr_37831 Neighboring gene STARR-seq mESC enhancer starr_37832 Neighboring gene STARR-seq mESC enhancer starr_37833 Neighboring gene STARR-seq mESC enhancer starr_37834 Neighboring gene STARR-seq mESC enhancer starr_37835 Neighboring gene STARR-seq mESC enhancer starr_37836 Neighboring gene STARR-seq mESC enhancer starr_37837 Neighboring gene complement component 6 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables phosphoric diester hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables phosphoric diester hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in lipid catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in glutamatergic synapse EXP
    Inferred from Experiment
    more info
    PubMed 
    is_active_in glutamatergic synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in synapse EXP
    Inferred from Experiment
    more info
    PubMed 
    is_active_in synapse IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    PI-PLC X domain-containing protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177355.3NP_796329.2  PI-PLC X domain-containing protein 3

      See identical proteins and their annotated locations for NP_796329.2

      Status: VALIDATED

      Source sequence(s)
      AC113957, AK038575, AK044972, BE945500
      Consensus CDS
      CCDS27362.2
      UniProtKB/Swiss-Prot
      Q8BLJ3, Q8BYR3
      UniProtKB/TrEMBL
      G3X9A7
      Related
      ENSMUSP00000053553.5, ENSMUST00000061925.5
      Conserved Domains (1) summary
      cd08616
      Location:19311
      PI-PLCXD1c; Catalytic domain of phosphatidylinositol-specific phospholipase C, X domain containing 1

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      4404973..4605067
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)