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    thiM hydroxyethylthiazole kinase [ Clostridium tetani E88 ]

    Gene ID: 24253408, updated on 31-Mar-2024

    Summary

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    Gene symbol
    thiM
    Gene description
    hydroxyethylthiazole kinase
    Locus tag
    CTC_RS09080
    Gene type
    protein coding
    Organism
    Clostridium tetani E88 (strain: Massachusetts, substrain: E88)
    Lineage
    Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Clostridium
    Old locus tag
    CTC01752; CTC_01752
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    Genomic context

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    Sequence:
    NC_004557.1 (1864475..1865299, complement)

    NC_004557.1Genomic Context describing neighboring genes Neighboring gene thiamine biosynthesis protein ThiF Neighboring gene sulfur carrier protein ThiS Neighboring gene thiamine phosphate synthase Neighboring gene bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase Neighboring gene energy coupling factor transporter S component ThiW

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_004557.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Crystal structure of 4-methyl-5-beta-hydroxyethylthiazole kinase from Bacillus subtilis at 1.5 A resolution. Campobasso N, et al. Biochemistry, 2000 Jul 11. PMID 10891066
    2. Structure of ThiM from Vitamin B1 biosynthetic pathway of Staphylococcus aureus - Insights into a novel pro-drug approach addressing MRSA infections. Drebes J, et al. Sci Rep, 2016 Mar 10. PMID 26960569, Free PMC Article
    3. The genome sequence of Clostridium tetani, the causative agent of tetanus disease. Bruggemann H, et al. Proc Natl Acad Sci U S A, 2003 Feb 4. PMID 12552129, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    General protein information

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    Preferred Names
    hydroxyethylthiazole kinase
    WP_011099943.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004557.1 Reference assembly

      Range
      1864475..1865299 complement
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      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_011099943.1 hydroxyethylthiazole kinase [Clostridium tetani]

      See identical proteins and their annotated locations for WP_011099943.1

      UniProtKB/Swiss-Prot
      Q893Q9
      Conserved Domains (1) summary
      PRK09355
      Location:6 → 271
      PRK09355; hydroxyethylthiazole kinase; Validated
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q893Q9.1

    Gene LinkOut

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