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    Zfp933 zinc finger protein 933 [ Mus musculus (house mouse) ]

    Gene ID: 242747, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp933provided by MGI
    Official Full Name
    zinc finger protein 933provided by MGI
    Primary source
    MGI:MGI:1922865
    See related
    Ensembl:ENSMUSG00000059423 AllianceGenome:MGI:1922865
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2810408P10Rik
    Summary
    Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Is expressed in forelimb bud. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in cerebellum adult (RPKM 2.6), frontal lobe adult (RPKM 2.5) and 23 other tissues See more
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    Genomic context

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    See Zfp933 in Genome Data Viewer
    Location:
    4 E1; 4 78.56 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (147906184..147933583, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (147822986..147849126, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene predicted gene 13148 Neighboring gene STARR-positive B cell enhancer mm9_chr4:147131061-147131362 Neighboring gene STARR-positive B cell enhancer mm9_chr4:147137358-147137659 Neighboring gene zinc finger protein 984 Neighboring gene STARR-positive B cell enhancer mm9_chr4:147149499-147149800 Neighboring gene STARR-positive B cell enhancer mm9_chr4:147153946-147154247 Neighboring gene STARR-positive B cell enhancer ABC_E4724 Neighboring gene STARR-positive B cell enhancer ABC_E9623 Neighboring gene STARR-positive B cell enhancer ABC_E6282 Neighboring gene STARR-seq mESC enhancer starr_12061 Neighboring gene STARR-positive B cell enhancer mm9_chr4:147185666-147185967 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:147187429-147187616 Neighboring gene STARR-positive B cell enhancer mm9_chr4:147188614-147188915 Neighboring gene ribosomal protein S19, pseudogene 3 Neighboring gene STARR-positive B cell enhancer ABC_E4726 Neighboring gene STARR-positive B cell enhancer ABC_E181 Neighboring gene migration and invasion inhibitory protein Neighboring gene Friend virus susceptibility 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Spatiotemporal regulation of GLI target genes in the mammalian limb bud. Lewandowski JP, et al. Dev Biol, 2015 Oct 1. PMID 26238476, Free PMC Article
    2. USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities. Liu C, et al. Sci Adv, 2023 May 19. PMID 37196079, Free PMC Article
    3. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
    4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Clone Names

    • MGC67181

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC242747
    Names
    zinc finger-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001355730.1 → NP_001342659.1  uncharacterized protein LOC242747 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL607066, BC058101, CB525762
      Conserved Domains (2) summary
      COG5048
      Location:125 → 435
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:353 → 373
      ZF_C2H2; C2H2 Zn finger [structural motif]

    2. NM_198619.3 → NP_941021.1  uncharacterized protein LOC242747 isoform 1

      See identical proteins and their annotated locations for NP_941021.1

      Status: VALIDATED

      Source sequence(s)
      AL607066, BC058101, CB525762
      Consensus CDS
      CCDS38963.1
      UniProtKB/TrEMBL
      Q6PEE4
      Related
      ENSMUSP00000101343.2, ENSMUST00000105718.8
      Conserved Domains (5) summary
      smart00349
      Location:4 → 45
      KRAB; krueppel associated box
      COG5048
      Location:157 → 467
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:385 → 405
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:4 → 40
      KRAB; KRAB box
      pfam13465
      Location:146 → 170
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      147906184..147933583 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030253575.2 → XP_030109435.1  uncharacterized protein LOC242747 isoform X1

      Conserved Domains (2) summary
      COG5048
      Location:125 → 435
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:353 → 373
      ZF_C2H2; C2H2 Zn finger [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version

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