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    mat1-Mc M-specific transcription factor Mc [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539619, updated on 18-Sep-2024

    Summary

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    Official Symbol
    mat1-Mc
    Official Full Name
    M-specific transcription factor Mc
    Primary source
    PomBase:SPBC23G7.09
    Locus tag
    SPOM_SPBC23G7.09
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    mat1Mc; matMc
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    Genomic context

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    See mat1-Mc in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (2114482..2115027)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene Rho-type GTPase-activating protein Rga7 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene M-specific transcription factor Mi Neighboring gene ncRNA Neighboring gene NADH-dependent flavin oxidoreductase Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Schizosaccharomyces pombe mating-type gene mat-Mc encodes a sequence-specific DNA-binding high mobility group box protein. Dooijes D, et al. J Biol Chem, 1993 Nov 25. PMID 8227043
    2. Two-step activation of meiosis by the mat1 locus in Schizosaccharomyces pombe. Willer M, et al. Mol Cell Biol, 1995 Sep. PMID 7651414, Free PMC Article
    3. Four mating-type genes control sexual differentiation in the fission yeast. Kelly M, et al. EMBO J, 1988 May. PMID 2900761, Free PMC Article
    4. Sequence-specific high mobility group box factors recognize 10-12-base pair minor groove motifs. van Beest M, et al. J Biol Chem, 2000 Sep 1. PMID 10867006
    5. Cell differentiation by interaction of two HMG-box proteins: Mat1-Mc activates M cell-specific genes in S.pombe by recruiting the ubiquitous transcription factor Ste11 to weak binding sites. Kjaerulff S, et al. EMBO J, 1997 Jul 1. PMID 9233811, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding, bending IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables sequence-specific DNA binding, bending IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables transcription coactivator activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in induction of conjugation with cellular fusion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mating type determination NAS
    Non-traceable Author Statement
    more info
    		  
    involved_in positive regulation of induction of conjugation with cellular fusion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of meiotic cell cycle IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of RNA polymerase II transcription regulator complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    is_active_in chromatin EXP
    Inferred from Experiment
    more info
    		 PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    M-specific transcription factor Mc

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      2114482..2115027
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021773.3 → NP_595867.1  M-specific transcription factor Mc [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595867.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      C7U331, P0CY16, P0CY17, P10840, Q9URE7
      Conserved Domains (1) summary
      cd01389
      Location:102 → 178
      MATA_HMG-box; MATA_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include the fungal mating type gene products MC, ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    C7U331.1

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    Research Materials