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    csn1 COP9/signalosome complex subunit Csn1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540352, updated on 18-Sep-2024

    Summary

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    Official Symbol
    csn1
    Official Full Name
    COP9/signalosome complex subunit Csn1
    Primary source
    PomBase:SPBC215.03c
    Locus tag
    SPOM_SPBC215.03C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See csn1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    4
    Sequence:
    Chromosome: II; NC_003423.3 (4027314..4029589, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene GTPase-activating protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene prefoldin subunit 5 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene heterotrimeric G protein gamma subunit Git11

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Fission yeast COP9/signalosome suppresses cullin activity through recruitment of the deubiquitylating enzyme Ubp12p. Zhou C, et al. Mol Cell, 2003 Apr. PMID 12718879
    2. The fission yeast COP9/signalosome is involved in cullin modification by ubiquitin-related Ned8p. Zhou C, et al. BMC Biochem, 2001. PMID 11504566, Free PMC Article
    3. Meiotic nuclear movements in fission yeast are regulated by the transcription factor Mei4 downstream of a Cds1-dependent replication checkpoint pathway. Ruan K, et al. Genes Cells, 2015 Mar. PMID 25492408, Free PMC Article
    4. Spd2 assists Spd1 in the modulation of ribonucleotide reductase architecture but does not regulate deoxynucleotide pools. Vejrup-Hansen R, et al. J Cell Sci, 2014 Jun 1. PMID 24652833
    5. Deletion mutants in COP9/signalosome subunits in fission yeast Schizosaccharomyces pombe display distinct phenotypes. Mundt KE, et al. Mol Biol Cell, 2002 Feb. PMID 11854407, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA damage response IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein deneddylation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of COP9 signalosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    COP9/signalosome complex subunit Csn1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      4027314..4029589 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022603.3 → NP_596680.1  COP9/signalosome complex subunit Csn1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596680.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O94308, Q9USF8
      Conserved Domains (2) summary
      pfam01399
      Location:262 → 365
      PCI; PCI domain
      pfam10602
      Location:77 → 246
      RPN7; 26S proteasome subunit RPN7
    Nucleotide Protein
    Heading Accession and Version

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