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    nse6 Smc5-6 complex non-SMC subunit Nse6 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541512, updated on 18-Sep-2024

    Summary

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    Official Symbol
    nse6
    Official Full Name
    Smc5-6 complex non-SMC subunit Nse6
    Primary source
    PomBase:SPAC11E3.08c
    Locus tag
    SPOM_SPAC11E3.08C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    cor1
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    Genomic context

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    See nse6 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (5296049..5297780, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene SEA complex subunit Sea3 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene DNA-binding transcription factor, MADS-box Map1 Neighboring gene ncRNA Neighboring gene V-type ATPase V1 subunit E Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene protein tyrosine phosphatase Pyp3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Smc5-Smc6 DNA repair complex. bridging of the Smc5-Smc6 heads by the KLEISIN, Nse4, and non-Kleisin subunits. Palecek J, et al. J Biol Chem, 2006 Dec 1. PMID 17005570
    2. Brc1 Promotes the Focal Accumulation and SUMO Ligase Activity of Smc5-Smc6 during Replication Stress. Oravcová M, et al. Mol Cell Biol, 2019 Jan 15. PMID 30348841, Free PMC Article
    3. Meiotic DNA joint molecule resolution depends on Nse5-Nse6 of the Smc5-Smc6 holocomplex. Wehrkamp-Richter S, et al. Nucleic Acids Res, 2012 Oct. PMID 22855558, Free PMC Article
    4. The RecQ4 orthologue Hrq1 is critical for DNA interstrand cross-link repair and genome stability in fission yeast. Groocock LM, et al. Mol Cell Biol, 2012 Jan. PMID 22064477, Free PMC Article
    5. SUMO-targeted ubiquitin ligases in genome stability. Prudden J, et al. EMBO J, 2007 Sep 19. PMID 17762865, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables chromatin-protein adaptor activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA damage response IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in double-strand break repair EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in double-strand break repair via homologous recombination IC
    Inferred by Curator
    more info
    		  
    Component Evidence Code Pubs
    part_of Smc5-Smc6 complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    Smc5-6 complex non-SMC subunit Nse6

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      5296049..5297780 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020364.3 → NP_594933.1  Smc5-6 complex non-SMC subunit Nse6 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594933.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O13688
      Conserved Domains (1) summary
      pfam08691
      Location:1 → 478
      Nse5; DNA repair proteins Nse5 and Nse6
    Nucleotide Protein
    Heading Accession and Version

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