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    kap104 karyopherin/importin beta family nuclear import signal receptor Kap104 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542046, updated on 18-Sep-2024

    Summary

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    Official Symbol
    kap104
    Official Full Name
    karyopherin/importin beta family nuclear import signal receptor Kap104
    Primary source
    PomBase:SPAC2F3.06c
    Locus tag
    SPOM_SPAC2F3.06C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See kap104 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003424.3 (3930533..3934101, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene xylose and arabinose reductase Neighboring gene ncRNA Neighboring gene single-strand DNA-binding protein Rim1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene plasma membrane sucrose/maltose:proton symporter Sut1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A proline-tyrosine nuclear localization signal (PY-NLS) is required for the nuclear import of fission yeast PAB2, but not of human PABPN1. Mallet PL, et al. Traffic, 2013 Mar. PMID 23279110
    2. Identification of genes encoding putative nucleoporins and transport factors in the fission yeast Schizosaccharomyces pombe: a deletion analysis. Chen XQ, et al. Yeast, 2004 Apr 30. PMID 15116432
    3. Nucleocytoplasmic transport in the midzone membrane domain controls yeast mitotic spindle disassembly. Lucena R, et al. J Cell Biol, 2015 May 11. PMID 25963819, Free PMC Article
    4. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
    5. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Kap104 mediates nuclear import of Pab2.
      Title: A proline-tyrosine nuclear localization signal (PY-NLS) is required for the nuclear import of fission yeast PAB2, but not of human PABPN1.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables GTP binding NAS
    Non-traceable Author Statement
    more info
    		  
    enables nuclear import signal receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables nuclear localization sequence binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein import into nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol HDA PubMed 
    is_active_in mitotic spindle midzone IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nuclear envelope HDA PubMed 
    is_active_in nuclear periphery IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    karyopherin/importin beta family nuclear import signal receptor Kap104

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      3930533..3934101 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019806.3 → NP_594385.1  karyopherin/importin beta family nuclear import signal receptor Kap104 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594385.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O14089
      Conserved Domains (5) summary
      COG5215
      Location:65 → 791
      KAP95; Karyopherin (importin) beta [Intracellular trafficking and secretion]
      cd00020
      Location:130 → 243
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      pfam13513
      Location:428 → 482
      HEAT_EZ; HEAT-like repeat
      sd00044
      Location:132 → 160
      HEAT; HEAT repeat [structural motif]
      cl04271
      Location:34 → 78
      IBN_N; Importin-beta N-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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