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    yhb1 nitric oxide dioxygenase [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542104, updated on 18-Sep-2024

    Summary

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    Official Symbol
    yhb1
    Official Full Name
    nitric oxide dioxygenase
    Primary source
    PomBase:SPAC869.02c
    Locus tag
    SPOM_SPAC869.02C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See yhb1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (5517951..5519950)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene amidase Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The flavohemoglobin Yhb1 is a new interacting partner of the heme transporter Str3. Ping FLY, et al. Mol Microbiol, 2024 Jul. PMID 38778742
    2. Nitric oxide signaling and its role in oxidative stress response in Schizosaccharomyces pombe. Astuti RI, et al. Nitric Oxide, 2016 Jan 30. PMID 26645666
    3. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article
    4. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
    5. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The flavohemoglobin Yhb1 is a new interacting partner of the heme transporter Str3.
      Title: The flavohemoglobin Yhb1 is a new interacting partner of the heme transporter Str3.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables FAD binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nitric oxide dioxygenase NAD(P)H activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables oxygen binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cellular detoxification of nitrogen compound IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in cellular response to nitrosative stress IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cellular response to nitrosative stress IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in nitric oxide catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol HDA PubMed 
    is_active_in mitochondrion IC
    Inferred by Curator
    more info
    		  
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    nitric oxide dioxygenase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      5517951..5519950
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020448.3 → NP_595017.1  nitric oxide dioxygenase [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595017.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9URY5
      Conserved Domains (3) summary
      cd06184
      Location:175 → 424
      flavohem_like_fad_nad_binding; FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The ...
      COG1017
      Location:30 → 179
      Hmp; Hemoglobin-like flavoprotein [Energy production and conversion]
      PRK13289
      Location:31 → 424
      PRK13289; bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional
    Nucleotide Protein
    Heading Accession and Version

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